Evidence map›Paper›PMID 38443762›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2024

The brain's "dark energy" puzzle: How strongly is glucose metabolism linked to resting-state brain activity?

Tommaso Volpi, Erica Silvestri, Marco Aiello, John J Lee, Andrei G Vlassenko, Manu S Goyal, Maurizio Corbetta, Alessandra Bertoldo

Abstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. The molecular and cellular underpinnings of human brain lateralization.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tommaso VolpiPadova Neuroscience Center, University of Padova, Padova, Italy.ORCID 0000-0002-5451-6710
Erica SilvestriDepartment of Information Engineering, University of Padova, Padova, Italy.
Marco AielloIRCCS SDN, 80143, Naples, Italy.
John J LeeNeuroimaging Laboratories at the Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0003-2269-6267
Andrei G VlassenkoNeuroimaging Laboratories at the Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, USA.
Manu S GoyalNeuroimaging Laboratories at the Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO, USA.ORCID 0000-0003-1970-4270
Maurizio CorbettaPadova Neuroscience Center, University of Padova, Padova, Italy.
Alessandra BertoldoPadova Neuroscience Center, University of Padova, Padova, Italy.

Funding

Aerobic Glycolysis in the Development ofAlzheimer's DiseaseR01AG053503 · NIA · WASHINGTON UNIVERSITY · PI RAICHLE, MARCUS E, VLASSENKO, ANDREI G. · 2017 to 2021
$4.1M
Aerobic Glycolysis: A Marker of BrainResilience to Aging and Alzheimer's DiseaseR01AG057536 · NIA · WASHINGTON UNIVERSITY · PI GOYAL, MANU S, VLASSENKO, ANDREI G. · 2017 to 2021
$3.7M
NIA NIH HHS R01 AG053503NIA NIH HHS R01 AG057536
6 · The paper itself

Abstract

Brain glucose metabolism, which can be investigated at the macroscale level with [

Indexed as

BrainGlucoseMagnetic Resonance ImagingAdultBrain MappingEnergy MetabolismFemaleFluorodeoxyglucose F18HumansMalePositron-Emission TomographyRestYoung AdultFluorodeoxyglucose F18Glucose[18F]FDG PETBrain glucose metabolismfunctional-metabolic modelmultilevel modelingspontaneous activity

Identifiers

PMID38443762
PMCPMC11342718

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.