Evidence map›Paper›PMID 38443706›Full record

ArticleBone marrow transplantation2024

Harmonizing definitions for hematopoietic recovery, graft rejection, graft failure, poor graft function, and donor chimerism in allogeneic hematopoietic cell transplantation: a report on behalf of the EBMT, ASTCT, CIBMTR, and APBMT.

Anna Sureda, Paul A Carpenter, Andrea Bacigalupo, Vijaya Raj Bhatt, Josu de la Fuente, Aloysius Ho, Leslie Kean, Jong Wook Lee, Isabel Sánchez-Ortega, Bipin N Savani and 12 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Bone marrow transplantation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
23.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 51 citations in OpenAlex.

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  16. Review
  17. Mapping Hematopoietic Fate after Transplantation.Stem cell reviews and reports · 2025
    Review
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  19. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors at 20 institutions in 9 countries.

Anna SuredaClinical Hematology Department, Institut Català d'Oncologia-L'Hospitalet, IDIBELL, Universitat de Barcelona, Barcelona, Spain. asureda@iconcologia.net.ORCID 0000-0002-1238-6970
Paul A CarpenterClinical Research Division, Fred Hutchinson Cancer Center, Seattle, WA, USA.
Andrea BacigalupoFondazione Policlinico Universitario A. Gemelli IRCCS, Roma, Italy.
Vijaya Raj BhattFred & Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA.ORCID 0000-0003-2513-0533
Josu de la FuenteDepartment of Paediatrics, Imperial College Healthcare NHS Trust, St Mary's Hospital, London, UK.ORCID 0000-0002-0974-1249
Aloysius HoDepartment of Haematology, Singapore General Hospital and National Cancer Centre Singapore, Singapore, Singapore.
Leslie KeanStem Cell Transplantation Program. Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA, USA.ORCID 0000-0003-0475-3926
Jong Wook LeeDivision of Hematology, Seoul St. Mary's Hospital, The Catholic University of Korea, Seoul, Republic of Korea.ORCID 0000-0003-2949-4166
Isabel Sánchez-OrtegaEBMT Medical officer, EBMT executive office, Barcelona, Spain.ORCID 0009-0005-5519-9154
Bipin N SavaniDivision of Hematology/ Oncology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA.ORCID 0000-0002-3304-9965
Johannes ScheteligMedical Department I, University Hospital Carl Gustav Carus. TU Dresden & DKMS Group, Clinical Trials Unit, Dresden, Germany.ORCID 0000-0002-2780-2981
Edward A StadtmauerPerelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Yoshiyuki TakahashiDepartment of Pediatrics, Nagoya University Graduate School of Medicine, Aichi, Japan.
Yoshiko AtsutaJapanese Data Center for Hematopoietic Cell Transplantation, Nagakute, Japan.ORCID 0000-0003-4404-2870
John KorethDepartment of Medical Oncology, Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Boston, MA, USA.
Nicolaus KrögerDepartment for Stem Cell Transplantation, University Medical Center Hamburg, Hamburg, Germany.ORCID 0000-0001-5103-9966
Per LjungmanDepartment. of Cellular Therapy and Allogeneic Stem Cell Transplantation. Karolinska Comprehensive Cancer Center, Karolinska University Hospital Huddinge, Division of Hematology, Department of Medicine Huddinge, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-8281-3245
Shinichiro OkamotoDivision of Hematology, Department of Medicine, Keio University School of Medicine, Tokyo, Japan.
Uday PopatDepartment of Stem Cell Transplantation & Cellular Therapy, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0002-7592-2224
Robert SoifferDepartment of Medical Oncology, Division of Hematologic Malignancies, Dana-Farber Cancer Institute, Boston, MA, USA.ORCID 0000-0002-5810-1192
Heather E StefanskiCenter for International Blood and Marrow Transplant Research, National Marrow Donor Program/Be The Match, Minneapolis, MN, USA.
Mohamed A Kharfan-DabajaDivision of Hematology-Oncology and Blood and Marrow Transplantation and Cellular Therapy Program, Mayo Clinic, Jacksonville, FL, USA.ORCID 0000-0001-7394-5185
Dana-Farber Cancer Institute · USAgostino Gemelli University Polyclinic · ITAichi Medical University · JPBoston Children's Hospital · USFred Hutch Cancer Center · USImperial College Healthcare NHS Trust · GBInstitut Català d'Oncologia · ESKarolinska University Hospital · SEKeio University · JPMayo Clinic in Florida · USNagoya University · JPNational Marrow Donor Program · USSingapore General Hospital · SGThe Catholic University of Korea Seoul St. Mary's Hospital · KRThe University of Texas MD Anderson Cancer Center · USUniversität Hamburg · DEUniversity Hospital Carl Gustav Carus · DEUniversity of Nebraska Medical Center · USUniversity of Pennsylvania · USVanderbilt University Medical Center · US

Funding

Data Resource for Analyzing Blood &Marrow TransplantsU24CA076518 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI Amy M Moskop, Bronwen Shaw · 1998 to 2026
$105.2M
NCI NIH HHS U24 CA076518
6 · The paper itself

Abstract

Despite emergence of novel therapies to treat hematologic malignancies, allogeneic hematopoietic cell transplantation (allo-HCT) remains an essential treatment modality capable of curing these diseases. Allo-HCT has been also shown to be curative in benign hematologic disorders such as aplastic anemia, sickle cell disease, and thalassemia, among others. Recently, the American Society for Transplantation and Cellular Therapy (ASTCT) published standardized definitions for hematopoietic recovery, graft rejection, graft failure, poor graft function, and donor chimerism. To attempt broader international consensus, a panel of adult and pediatric physician transplant experts was assembled from European Society for Blood and Marrow Transplantation (EBMT), ASTCT, the Center for International Blood and Marrow Transplant Research (CIBMTR), and Asia-Pacific Blood and Marrow Transplantation (APBMT). Consensus was defined as ≥70% of voting members strongly agreeing or somewhat agreeing with a definition. With few exceptions, there was a consensus to endorse the prior ASTCT definitions. Importantly, we revised existing EBMT and CIBMTR data collection forms to align with these harmonized definitions that will facilitate research and international collaboration among transplant researchers and across transplant registries.

Indexed as

Graft RejectionHematopoietic Stem Cell TransplantationAdultAllograftsFemaleHumansMaleTransplantation ChimeraTransplantation, Homologous

Identifiers

PMID38443706
PMCPMC11161398
OpenAlexW4392450786

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.