ReviewNature reviews. Neuroscience2024
Preparatory activity and the expansive null-space.
Review in Nature reviews. Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
71 citing papers in PubMed.
- Speech motor cortex enables BCI cursor control and click.Journal of neural engineering · 2025Trial
- Article
- Orbitofrontal value dynamics and striatal population geometry during interruption of automatic behavior.Neuron · 2026Article
- Review
- Neuromotor modules revealed by direct electrical stimulation of the human primary motor cortex.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Temporally structured motor and auditory representations in covert syllable production.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Temporal Indexing of Motor Memory.bioRxiv : the preprint server for biology · 2026Article
- Preparatory encoding of intended movement in the human motor cortex and implications for brain-computer interfaces.Current biology : CB · 2026Article
- Anticipatory organization of neural population dynamics speeds behavioral decisions.bioRxiv : the preprint server for biology · 2026Article
- Sparse component analysis: A method that uncovers separable computations within neural population activity.Neuron · 2026Article
- Sensory-to-motor transformations: From serial pipelines to dynamic, distributed processes.Neuroscience and biobehavioral reviews · 2026Review
- Article
- Stable readout of visual representations mediates flexible generalization.Nature communications · 2026Article
- Distinct temporal patterns of beta bursts differentiate successful and failed movement cancellation.iScience · 2026Article
- Brain-wide arousal signals are segregated from movement planning in the superior colliculus of the macaque.eLife · 2026Article
- Audiomotor prediction errors drive speech adaptation even in the absence of overt movement.PLoS biology · 2026Article
- Contextual gating of whisker-evoked responses by frontal cortex supports flexible decision making.Nature communications · 2026Article
- Article
- Premotor cortex uses a compositional neural geometry to plan words.bioRxiv : the preprint server for biology · 2026Article
- Parkinsonism disrupts the population-level organization of cortical dynamics.bioRxiv : the preprint server for biology · 2026Article
11 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
The study of the cortical control of movement experienced a conceptual shift over recent decades, as the basic currency of understanding shifted from single-neuron tuning towards population-level factors and their dynamics. This transition was informed by a maturing understanding of recurrent networks, where mechanism is often characterized in terms of population-level factors. By estimating factors from data, experimenters could test network-inspired hypotheses. Central to such hypotheses are 'output-null' factors that do not directly drive motor outputs yet are essential to the overall computation. In this Review, we highlight how the hypothesis of output-null factors was motivated by the venerable observation that motor-cortex neurons are active during movement preparation, well before movement begins. We discuss how output-null factors then became similarly central to understanding neural activity during movement. We discuss how this conceptual framework provided key analysis tools, making it possible for experimenters to address long-standing questions regarding motor control. We highlight an intriguing trend: as experimental and theoretical discoveries accumulate, the range of computational roles hypothesized to be subserved by output-null factors continues to expand.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.