Observational studyDrug safety2024
Risk Factors Associated with Medication Administration Errors in Children: A Prospective Direct Observational Study of Paediatric Inpatients.
Observational study in Drug safety, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.
- Medication-related problems and their associated factors among paediatric patients in Ethiopia: a systematic review and meta-analysis.BMJ paediatrics open · 2026Pooled it
- Does the accuracy of medication administration documentation improve with electronic medication systems? A stepped-wedge cluster randomised trial.BMJ health & care informatics · 2026Trial
- Unintentional Incorrect Route of Drug Administration: An Analysis of Spontaneous Reports of Medication Errors in Children and Adolescents from Germany.Paediatric drugs · 2026Article
- Pediatric medication-related incidents in Japan: a nationwide observational study of severity and factors associated with severe patient harm.European journal of pediatrics · 2026Observational
- How Nurses Maintain High-Risk Medication Safety in Paediatric Intensive Care.Nursing in critical care · 2026Article
- Breaking the safety barrier: Risk factors for unjustified non-acceptance of pharmaceutical interventions in the PICU and their association with mortality.Exploratory research in clinical and social pharmacy · 2026Article
- Global Prevalence and Associated Factors of Medication Errors in Hospitalized Pediatric Patients: Systematic Review and Meta-Analysis.JMIR pediatrics and parenting · 2026Review
- Fear, silence, and moral injury following medication errors: insights from Jordanian pediatric nurses.BMC nursing · 2026Article
- Evaluation of Intravenous Administration of Anti-Infective Agents and Documentation Quality in Orthopedics and Trauma Surgery: A Quantitative Study on Discrepancies Between Physician Prescriptions and Nursing Records.Antibiotics (Basel, Switzerland) · 2026Article
- Harm to Children from Prescribing and Administration Errors in Acute Care: A Multidisciplinary Panel Assessment.Drug safety · 2026Article
- Preventing Medication Errors in Paediatrics: A Narrative Review.Clinical medicine insights. Pediatrics · 2026Review
- Factors associated with medication administration errors in hospitalized pediatric patients: A scoping review.Therapeutic advances in drug safety · 2026Article
- Computerized Physician Order Entry and Pediatric Prescribing Errors: A Multicenter Database Study.Drug, healthcare and patient safety · 2026Article
- Oral versus intravenous antibiotics: Oral antibiotics are more cost-effective and may be safer than intravenous antibiotics for most infections in stable adults.African journal of primary health care & family medicine · 2025Review
- Determining the self-evaluation levels of nursing students' competency in child patient safety.BMC nursing · 2025Article
- Article
- The Application and Efficacy of Medication Safety Officer-Based Multidisciplinary Management in Reducing Adverse Drug Reaction and Improving Intravenous Management.Risk management and healthcare policy · 2025Article
- Errors Associated With Medication Administration by a Nurse During Hospitalisation: A Prospective Observational Multicentric Study.Nursing open · 2025Observational
- How often do parents administer medications to their children in hospital? A prospective direct observational study.BMJ open quality · 2024Observational
- Decreasing Prescriber Errors in a Tertiary Care Pediatric Intensive Care Unit via QI Methodology.Pediatric quality & safetyArticle
Corrections and comments
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
Abstract
introductionLimited evidence exists regarding medication administration errors (MAEs) on general paediatric wards or associated risk factors exists.
objectiveThe aim of this study was to identify nurse, medication, and work-environment factors associated with MAEs among paediatric inpatients.
methodsThis was a prospective, direct observational study of 298 nurses in a paediatric referral hospital in Sydney, Australia. Trained observers recorded details of 5137 doses prepared and administered to 1530 children between 07:00 h and 22:00 h on weekdays and weekends. Observation data were compared with medication charts to identify errors. Clinical errors, potential severity and actual harm were assessed. Nurse characteristics (e.g. age, sex, experience), medication type (route, high-risk medications, use of solvent/diluent), and work variables (e.g. time of administration, weekday/weekend, use of an electronic medication management system [eMM], presence of a parent/carer) were collected. Multivariable models assessed MAE risk factors for any error, errors by route, potentially serious errors, and errors involving high-risk medication or causing actual harm.
resultsErrors occurred in 37.0% (n = 1899; 95% confidence interval [CI] 35.7-38.3) of administrations, 25.8% (n = 489; 95% CI 23.8-27.9) of which were rated as potentially serious. Intravenous infusions and injections had high error rates (64.7% [n = 514], 95% CI 61.3-68.0; and 77.4% [n = 188], 95% CI 71.7-82.2, respectively). For intravenous injections, 59.7% (95% CI 53.4-65.6) had potentially serious errors. No nurse characteristics were associated with MAEs. Intravenous route, early morning and weekend administrations, patient age ≥ 11 years, oral medications requiring solvents/diluents and eMM use were all significant risk factors. MAEs causing actual harm were 45% lower using an eMM compared with paper charts.
conclusionMedication error prevention strategies should target intravenous administrations and not neglect older children in hospital. Attention to nurses' work environments, including improved design and integration of medication technologies, is warranted.
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