Article in Leukemia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
2 citing papers in PubMed, 3 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
12 authors at 2 institutions in 1 country.
Jasmine C WongDepartment of Pediatrics, University of California, San Francisco, CA, USA.
Kelley M WeinfurtnerDepartment of Pediatrics, University of California, San Francisco, CA, USA.
Tamara WestoverDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID 0000-0002-1000-6698
Jangkyung KimDepartment of Pediatrics, University of California, San Francisco, CA, USA.
Eric J LebishDepartment of Pediatrics, University of California, San Francisco, CA, USA.
Maria Del Pilar AlzamoraDepartment of Pediatrics, University of California, San Francisco, CA, USA.
Benjamin J HuangDepartment of Pediatrics, University of California, San Francisco, CA, USA.ORCID 0000-0001-6996-0833
Michael WalshDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Sherif AbdelhamedDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.ORCID 0000-0002-3319-2403
Jing MaDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA.
Jeffery M KlcoDepartment of Pathology, St. Jude Children's Research Hospital, Memphis, TN, USA. Jeffery.klco@stjude.org.ORCID 0000-0003-2961-6960
Kevin ShannonDepartment of Pediatrics, University of California, San Francisco, CA, USA. Kevin.shannon@ucsf.edu.
University of California, San Francisco · USSt. Jude Children's Research Hospital · US
Funding
Viral Vector Technology (VVTSR)P30CA021765 · NCI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Gregory Armstrong · 1985 to 2026
$166.9M
Cellular and functional impact of SAMD9L mutations on hematopoiesis and myelodysplasiaR01HL144653 · NHLBI · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI KLCO, JEFFERY M · 2019 to 2023
$2.2M
In Vivo Functional Analysis of Chromosome 7q22 Deletions in Myeloid MalignanciesR01CA216352 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SHANNON, KEVIN M. · 2017 to 2021
$1.7M
Co-targeting BET Bromodomain Proteins and Aberrant Signaling in AML.K08CA256489 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUANG, BENJAMIN · 2021 to 2025
$1.2M
Biologic and Preclinical Studies of Myeloid MalignanciesR50CA211452 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI WONG, JASMINE CHING YING · 2016 to 2020
Monosomy 7 and del(7q) are among the most common and poorly understood genetic alterations in myelodysplastic neoplasms and acute myeloid leukemia. Chromosome band 7q22 is a minimally deleted segment in myeloid malignancies with a del(7q). However, the rarity of "second hit" mutations supports the idea that del(7q22) represents a contiguous gene syndrome. We generated mice harboring a 1.5 Mb germline deletion of chromosome band 5G2 syntenic to human 7q22 that removes Cux1 and 27 additional genes. Hematopoiesis is perturbed in 5G2
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
5G2 mutant mice model loss of a commonly deleted segment of chromosome 7q22 in myeloid malignancies. · full record | OpenQuestion