ArticlePediatric research2025
Global, regional, and national burden of type 1 diabetes in adolescents and young adults.
Article in Pediatric research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 70 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
70 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.
- Pooled it
- Bihormonal fully closed-loop glucose control in adolescents with Type 1 diabetes: an outpatient, randomized, crossover trial.Pediatric diabetes · 2026Trial
- Efficacy of Nurse-Led WIKAP Intervention on Hypoglycemia Coping Confidence and Outcomes in Adolescents with Type 1 Diabetes Mellitus: A Quasi-Experimental Study in Zhijiang, China.Patient preference and adherence · 2026Trial
- Co-transplantation of pancreatic islets with adipose-derived mesenchymal stem cells in vascularized kidney ECM scaffolds to restore type 1 diabetes mellitus.Bioactive materials · 2026Article
- Increasing incidence and clinical burden of paediatric type 1 diabetes in Italy: insights from a large administrative database.Acta diabetologica · 2026Article
- Exploring inequities in access to diabetes technologies among children and young people with type 1 diabetes: Perspectives of parents and young people from ethnic minority groups and low socio-economic areas.Diabetic medicine : a journal of the British Diabetic Association · 2026Article
- Trends in prevalence and incidence of diabetic retinal disease in patients with type 1 and type 2 diabetes mellitus.Journal of diabetes and its complications · 2026Article
- PEStimate: predicting offspring disease risk after polygenic embryo screening.Bioinformatics (Oxford, England) · 2026Article
- Divergent cell-type specific hypoxia responses in human stem cell-derived and primary islets.Scientific reports · 2026Article
- Clinical Profile of Diabetes Mellitus in Young Patients Admitted at BP Koirala Institute of Health Sciences: A Cross-Sectional Study.Health science reports · 2026Article
- Selenium-loaded sustained-release schizophyllan alleviates pancreatic and pulmonary inflammatory damage in type 1 diabetes mellitus by modulating gut microbiota and T cell balance.Journal of nanobiotechnology · 2026Article
- Real-Time Type 1 Diabetes Self-Management Decision-Making in Adolescents: Protocol for a Longitudinal Mixed Methods Study Using Text Messaging and Continuous Glucose Monitoring.JMIR research protocols · 2026Article
- Generalizability of Progression Risk in the TN-10 Trial to a European Population With or Without a First-Degree Relative With Type 1 Diabetes.Diabetes care · 2026Article
- Hypertension Subtypes and Diabetes: Joint Associations in the National Health and Nutrition Examination Survey.JACC. Advances · 2026Article
- Article
- Can we cure autoimmunity?Current opinion in immunology · 2026Review
- The Mediating Role of Perceived Social Support in Family Cohesion and Disease Identity Among Chinese Adolescents and Young Adults with Type 1 Diabetes Mellitus: A Cross-Sectional Study.Nursing reports (Pavia, Italy) · 2026Article
- Emotional Challenges Experienced along the Diabetes Technology Journey by Caregivers of Black and Hispanic/Latino Youth with Type 1 Diabetes.Hormone research in paediatrics · 2026Article
- Modulating immune response for the prevention and treatment of type 1 diabetes.Frontiers in immunology · 2026Review
- Artificial intelligence-driven therapeutics for disease modification in type 1 diabetes: a digital public health and clinical translation framework.Frontiers in public health · 2026Review
10 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundType 1 diabetes (T1D) incidence in adolescents varies widely, but has increased globally in recent years. This study reports T1D burden among adolescents and young adults aged 10-24-year-old age group at global, regional, and national levels.
methodsBased on the Global Burden of Disease Study 2019, we described the burden of T1D in the 10-24-year-old age group. We further analyzed these trends by age, sex, and the Social Development Index. Joinpoint regression analysis was used to assess temporal trends.
resultsT1D incidence among adolescents and young adults increased from 7·78 per 100,000 population (95% UI, 5·27-10·60) in 1990 to 11·07 per 100,000 population (95% UI, 7·42-15·34) in 2019. T1D mortality increased from 5701·19 (95% UI, 4642·70-6444·08) in 1990 to 6,123·04 (95% UI, 5321·82-6887·08) in 2019, representing a 7·40% increase in mortality. The European region had the highest T1D incidence in 2019. Middle-SDI countries exhibited the largest increase in T1D incidence between 1990 and 2019.
conclusionT1D is a growing health concern globally, and T1D burden more heavily affects countries with low SDI. Specific measures and effective collaboration among countries with different SDIs are required to improve diabetes care in adolescents. IMPACT: We assessed trends in T1D incidence and burden among youth in the 10-24-year-old age group by evaluating data from the Global Burden of Disease Study 2019. Our results demonstrated that global T1D incidence in this age group increased over the past 30 years, with the European region having the highest T1D incidence. Specific measures and effective collaboration among countries with different SDIs are required to improve diabetes care in adolescents.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.