Evidence map›Paper›PMID 38443142›Full record

GuidelineRespiratory care2024

AARC Clinical Practice Guideline: Spontaneous Breathing Trials for Liberation From Adult Mechanical Ventilation.

Karsten J Roberts, Lynda T Goodfellow, Corinne M Battey-Muse, Cheryl A Hoerr, Megan L Carreon, Morgan E Sorg, Joel Glogowski, Timothy D Girard, Neil R MacIntyre, Dean R Hess

3 registry-linked trialsAbstract readPractice Guideline
In one paragraph

Guideline in Respiratory care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06561295 narecruitingnot on this map

Impact of Spontaneous Breathing Trial Timing on Outcomes in Mechanically Ventilated Adult Patients

TypeinterventionalSponsorRush University Medical CenterRan2024 to 2026Enrolled348ConditionsRespiration, Artificial, WeaningArmsLater Morning Timing of Spontaneous Breathing Trials
NCT07005505 narecruitingnot on this mapstarted 2025, after this paper: background citation

Automatic Tube Compensation vs. Pressure Support Ventilation During Spontaneous Breathing Trials in Critically Ill Adults: A Cluster-Randomized, Cluster-Crossover Trial

TypeinterventionalSponsorRush University Medical CenterRan2025 to 2027Enrolled880ConditionsSpontaneous Breathing Trial in ICUArmsPressure Support Ventilation (PSV), Automatic tube compensation (ATC)
NCT07098611 recruitingnot on this mapstarted 2025, after this paper: background citation

A New Tool for Extubation Readiness in Mechanically Ventilated Patients: Readiness for EXtubation Score (REXs STUDY)

Typeobservational_patient_registrySponsorMedipol UniversityRan2025 to 2026Enrolled470ConditionsVentilator Weaning, Respiration, Artificial, Respiratory Failure, Extubation Readiness
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Review
  9. Review
  10. Article
  11. Observational
  12. Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Karsten J RobertsThomas Jefferson University, Philadelphia, Pennsylvania karsten.roberts@jefferson.edu.
Lynda T GoodfellowAmerican Association for Respiratory Care/Daedalus Enterprises, Irving, Texas; and Georgia State University, Atlanta, Georgia.
Corinne M Battey-MuseGeorgia State University, Atlanta, Georgia.
Cheryl A HoerrPhelps Health, Rolla, Missouri.
Megan L CarreonUT Health, San Antonio, Texas.
Morgan E SorgBoise State University, Boise, Idaho; and Bunnell, Inc, Salt Lake City, Utah.
Joel GlogowskiGeorgia State University, Atlanta, Georgia.
Timothy D GirardCenter for Research, Investigation, and Systems Modeling of Acute Illness, Department of Critical Care Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania.
Neil R MacIntyreDuke University Medical Center, Durham, North Carolina.
Dean R HessAmerican Association for Respiratory Care/Daedalus Enterprises, Irving, Texas; and Massachusetts General Hospital, Boston, Massachusetts.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite prior publications of clinical practice guidelines related to ventilator liberation, some questions remain unanswered. Many of these questions relate to the details of bedside implementation. We, therefore, formed a guidelines committee of individuals with experience and knowledge of ventilator liberation as well as a medical librarian. Using Grading of Recommendations Assessment, Development, and Evaluation (GRADE) methodology, we make the following recommendations: (1) We suggest that calculation of a rapid shallow breathing index is not needed to determine readiness for a spontaneous breathing trial (SBT) (conditional recommendation; moderate certainty); (2) We suggest that SBTs can be conducted with or without pressure support ventilation (conditional recommendation, moderate certainty); (3) We suggest a standardized approach to assessment and, if appropriate, completion of an SBT before noon each day (conditional recommendation, very low certainty); and (4) We suggest that F

Indexed as

Respiration, ArtificialVentilator WeaningAdultCritical IllnessHumansRespirationextubationliberationmechanical ventilationrapid shallow breathing indexspontaneous breathing trialsweaning

Identifiers

PMID38443142
PMCPMC11285503

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.