ArticleBritish journal of sports medicine2024
Do the associations of daily steps with mortality and incident cardiovascular disease differ by sedentary time levels? A device-based cohort study.
Article in British journal of sports medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Contextual factors associated with walking performance after stroke: a systematic review and meta-analysis.Frontiers in neurology · 2025Pooled it
- Effects of a dog activity tracker on owners' walking: a community-based randomised controlled trial.BMC research notes · 2024Trial
- Association of wearableZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2026Article
- Dose-response association between daily step count and health-related outcomes in older adults: a nationwide cross-sectional study in Thailand.BMC geriatrics · 2026Article
- Impact of physical activity patterns on major adverse cardiovascular events in adults with hypertension.British journal of sports medicine · 2026Article
- Characterising the impact of shift work on diet and glucose variability in healthcare employees living with type 2 diabetes: The Shift-Diabetes study.Diabetic medicine : a journal of the British Diabetic Association · 2026Article
- Daily steps offset risks of sedentary behavior in the All of Us research program.Nature communications · 2026Article
- Limitations of Daily Step Count for Assessing Health in Older Adults: The Need to Consider Walking Intensity.Epidemiologia (Basel, Switzerland) · 2026Article
- Vigorous intermittent lifestyle physical activity (VILPA) and mortality risk among US adults: a wearables-based national cohort study.The international journal of behavioral nutrition and physical activity · 2026Article
- The Association Between Sedentary Behavior and Cardiovascular Disease Risk: An Analysis Based on NHANES Data.Cardiovascular therapeutics · 2026Article
- The unsatisfactory state of physical activity and lifestyle among schoolchildren calls for changes in physical education teacher training.Frontiers in sports and active living · 2026Article
- Effects of the '10,000 Steps Duesseldorf' intervention promoting physical activity in community-dwelling adults: results of a nonrandomized controlled trial.The international journal of behavioral nutrition and physical activity · 2025Article
- "Weekend warrior" physical activity pattern and risk of incident cancer.Annals of medicine · 2025Article
- Relationship Between Activity Tracker Metrics and the Physical Activity Index and Their Association With Cardiometabolic Phenotypes, Subclinical Atherosclerosis, and Cardiac Remodeling: Cross-Sectional Study.JMIR mHealth and uHealth · 2025Article
- Physical activity moderates the mediating role of depression between experiential avoidance and Internet addiction.Scientific reports · 2025Article
- Biomarkers of aging: from molecules and surrogates to physiology and function.Physiological reviews · 2025Review
- Accelerometer-derived "weekend warrior" physical activity, sedentary behavior, and risk of dementia.Alzheimer's research & therapy · 2025Article
- Associations of daily step count with all-cause mortality and cardiovascular mortality in hypertensive US adults: a cohort study from NHANES 2005-2006.BMC public health · 2025Article
- Article
- Behavior change wheel as a tool to promote physical activity in online intervention: a case study.Frontiers in psychology · 2025Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study aims to examine the associations of daily step count with all-cause mortality and incident cardiovascular disease (CVD) by sedentary time levels and to determine if the minimal and optimal number of daily steps is modified by high sedentary time.
methodsUsing data from the UK Biobank, this was a prospective dose-response analysis of total daily steps across low (<10.5 hours/day) and high (≥10.5 hours/day) sedentary time (as defined by the inflection point of the adjusted absolute risk of sedentary time with the two outcomes). Mortality and incident CVD was ascertained through 31 October 2021.
resultsAmong 72 174 participants (age=61.1±7.8 years), 1633 deaths and 6190 CVD events occurred over 6.9 (±0.8) years of follow-up. Compared with the referent 2200 steps/day (5th percentile), the optimal dose (nadir of the curve) for all-cause mortality ranged between 9000 and 10 500 steps/day for high (HR (95% CI)=0.61 (0.51 to 0.73)) and low (0.69 (0.52 to 0.92)) sedentary time. For incident CVD, there was a subtle gradient of association by sedentary time level with the lowest risk observed at approximately 9700 steps/day for high (0.79 (0.72 to 0.86)) and low (0.71 (0.61 to 0.83)) sedentary time. The minimal dose (steps/day associated with 50% of the optimal dose) of daily steps was between 4000 and 4500 steps/day across sedentary time groups for all-cause mortality and incident CVD.
conclusionsAny amount of daily steps above the referent 2200 steps/day was associated with lower mortality and incident CVD risk, for low and high sedentary time. Accruing 9000-10 500 steps/day was associated with the lowest mortality risk independent of sedentary time. For a roughly equivalent number of steps/day, the risk of incident CVD was lower for low sedentary time compared with high sedentary time.
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