Evidence map›Paper›PMID 38442804›Full record

ArticleThe American journal of pathology2024

Deletion of MyD88 in T Cells Improves Antitumor Activity in Melanoma.

Abraham L Bayer, Darwing Padilla-Rolon, Sasha Smolgovsky, Philip W Hinds, Pilar Alcaide

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of pathology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. MyD88 determines T cell fate through BCAP-PI3K signaling.Journal of immunology (Baltimore, Md. : 1950) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Abraham L BayerDepartment of Immunology, Tufts University, Boston, Massachusetts.
Darwing Padilla-RolonDepartment of Immunology, Tufts University, Boston, Massachusetts.
Sasha SmolgovskyDepartment of Immunology, Tufts University, Boston, Massachusetts.
Philip W HindsDepartment of Genetics, Molecular and Cell Biology, Tufts University, Boston, Massachusetts.
Pilar AlcaideDepartment of Immunology, Tufts University, Boston, Massachusetts. Electronic address: pilar.alcaide@tufts.edu.
Tufts University · US

Funding

Mechanisms of T cell activation in cardiac fibrosis and non-ischemic heart failureR01HL144477 · NHLBI · TUFTS UNIVERSITY BOSTON · PI ALCAIDE ALONSO, MARIA PILAR · 2019 to 2023
$3.2M
Regulation of T cell immune response in Heart Failure with Preserved Ejection FractionR01HL165725 · NHLBI · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Maria Pilar Alcaide Alonso · 2023 to 2026
$2.5M
Building Diversity in Biomedical SciencesR25HL007785 · NHLBI · TUFTS UNIVERSITY BOSTON · PI MAGUIRE, JAMIE LYNN · 2008 to 2024
$2.0M
Comparing the role of MyD88 and TRIF in T-cell effector function and the development of heart failureF30HL162200 · NHLBI · TUFTS UNIVERSITY BOSTON · PI Abraham Bayer · 2022 to 2026
$238k
Characterizing mechanisms of T cell-mediated cardiac pathology in Heart Failure with Preserved Ejection FractionF31HL159907 · NHLBI · TUFTS UNIVERSITY BOSTON · PI SMOLGOVSKY, SANDRA · 2022 to 2023
$67k
NHLBI NIH HHS F30 HL162200NHLBI NIH HHS F31 HL159907NHLBI NIH HHS R01 HL144477NHLBI NIH HHS R01 HL165725NHLBI NIH HHS R25 HL007785
6 · The paper itself

Abstract

Cytotoxic CD8

Indexed as

CD8-Positive T-LymphocytesMyeloid Differentiation Factor 88AnimalsLymphocyte ActivationMelanomaMelanoma, ExperimentalMiceMice, Inbred C57BLMice, KnockoutTumor MicroenvironmentMyd88 protein, mouseMyeloid Differentiation Factor 88

Identifiers

PMID38442804
PMCPMC11156157
OpenAlexW4392342928

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.