Evidence map›Paper›PMID 38442727›Full record

ArticleCase reports in critical care2021

Combined Hyperglycemic Hyperosmolar Syndrome and Diabetic Ketoacidosis Associated with COVID-19 in a Pediatric Patient.

Yu Shan Tseng, Bradley Tilford, Usha Sethuraman, Katherine Cashen

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in critical care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Yu Shan TsengDepartment of Pediatrics, Division of Pediatric Critical Care, Children's Hospital of Michigan, Detroit, Michigan, USA.ORCID https://orcid.org/0000-0001-5513-424X
Bradley TilfordDepartment of Pediatrics, Division of Pediatric Critical Care, Central Michigan University/Children's Hospital of Michigan, Detroit, Michigan, USA.ORCID https://orcid.org/0000-0001-8823-4028
Usha SethuramanDepartment of Pediatrics, Division of Pediatric Emergency Medicine, Central Michigan University/Children's Hospital of Michigan, Detroit, Michigan, USA.ORCID https://orcid.org/0000-0002-5183-0325
Katherine CashenDepartment of Pediatrics, Division of Pediatric Critical Care, Central Michigan University/Children's Hospital of Michigan, Detroit, Michigan, USA.ORCID https://orcid.org/0000-0002-8854-5085
Central Michigan University · USChildren's Hospital of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although most children with coronavirus disease 2019 (COVID-19) are asymptomatic or only with mild symptoms, many symptomatic children still require admission to the intensive care unit. Multiple cases of diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic syndrome (HHS) associated with COVID-19 have been reported in adults. However, to our knowledge, only few similar cases have been published in the pediatric population. We report one of the first few severe cases of mixed HHS with DKA associated with COVID-19 in an adolescent. Our patient was successfully treated with intravenous immunoglobulin, Remdesivir, and methylprednisolone. As the pandemic continues, clinicians should be aware of this syndrome and consider early use of Remdesivir and corticosteroids. Further studies are required to understand the pathophysiology of this syndrome occurring with COVID-19.

Identifiers

PMID38442727
PMCPMC8627355
OpenAlexW3215027119

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.