Evidence map›Paper›PMID 38442302›Full record

ArticleAngewandte Chemie (International ed. in English)2024

"Off-Label Use" of the Siderophore Enterobactin Enables Targeted Imaging of Cancer with Radioactive Ti

Angus J Koller, Owen Glaser, Molly C DeLuca, Rachel N Motz, Edith K Amason, Imma Carbo-Bague, Jason C Mixdorf, Ilia A Guzei, Eduardo Aluicio-Sarduy, Dariusz Śmiłowicz and 5 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Kupyaphores─Self-Assembling Diisocyanolipopeptide ZnJournal of the American Chemical Society · 2025
    Article
  4. Towards the Stable Chelation of Radioantimony(V) for Targeted Auger Theranostics.Angewandte Chemie (International ed. in English) · 2025
    Article
  5. [ACS omega · 2025
    Article
  6. Re-evaluation of theBiochemistry · 2025
    Article
  7. Sustainable production of radionuclidically pure antimony-119.EJNMMI radiopharmacy and chemistry · 2024
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 2 countries.

Angus J KollerDepartment of Chemistry, Stony Brook University, Stony Brook, New York, 11794, United States.
Owen GlaserDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin, 53706, United States.
Molly C DeLucaDepartment of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, Wisconsin, 53705, United States.
Rachel N MotzDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States.
Edith K AmasonDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin, 53706, United States.
Imma Carbo-BagueDepartment of Chemistry, Simon Fraser University, Burnaby, British Columbia, V5A 1S6, Canada.
Jason C MixdorfDepartment of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, Wisconsin, 53705, United States.
Ilia A GuzeiDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin, 53706, United States.
Eduardo Aluicio-SarduyDepartment of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, Wisconsin, 53705, United States.
Dariusz ŚmiłowiczDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin, 53706, United States.
Todd E BarnhartDepartment of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, Wisconsin, 53705, United States.
Caterina F RamogidaDepartment of Chemistry, Simon Fraser University, Burnaby, British Columbia, V5A 1S6, Canada.
Elizabeth M NolanDepartment of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts, 02139, United States.
Jonathan W EngleDepartment of Medical Physics, University of Wisconsin-Madison, 1111 Highland Avenue, Madison, Wisconsin, 53705, United States.
Eszter BorosDepartment of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, Wisconsin, 53706, United States.ORCID 0000-0002-4186-6586
University of Wisconsin–Madison · USMassachusetts Institute of Technology · USSimon Fraser University · CAStony Brook University · US

Funding

Harnessing iron acquisition to hinder enterobacterial pathogenesisR01AI176390 · NIAID · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Elizabeth M Nolan, Manuela Raffatellu · 2023 to 2026
$2.9M
QExactive (Orbitrap) mass spectrometerS10OD020022 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI VESTLING, MARTHA M · 2015 to 2015
$483k
NIAID NIH HHS R01 AI176390NIGMS NIH HHS 1S10 OD020022NIH HHS S10 OD020022
6 · The paper itself

Abstract

The development of inert, biocompatible chelation methods is required to harness the emerging positron emitting radionuclide

Indexed as

Prostatic NeoplasmsSiderophoresAnimalsEnterobactinHumansMaleMiceOff-Label UseRadioisotopesTitaniumEnterobactinRadioisotopesSiderophoresTitaniumcatecholimagingpositronsiderophoretitanium

Identifiers

PMID38442302
PMCPMC11258920
OpenAlexW4392448241

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.