Evidence map›Paper›PMID 38442291›Full record

ArticleEuropean heart journal2024

Inhibition of miR-21: cardioprotective effects in human failing myocardium ex vivo.

Naisam Abbas, Jonas A Haas, Ke Xiao, Maximilian Fuchs, Annette Just, Andreas Pich, Filippo Perbellini, Christopher Werlein, Fabio Ius, Arjang Ruhparwar and 3 more

Open access · hybridAbstract read
In one paragraph

Article in European heart journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  10. Living myocardial slices as a model for testing cardiac pro-reparative gene therapies.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  11. Article
  12. miRNA discovery to therapy: The field is sufficiently mature to assess the value of miRNA-based therapeutics.Molecular therapy : the journal of the American Society of Gene Therapy · 2025
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Naisam AbbasInstitute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.
Jonas A HaasInstitute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.
Ke XiaoFraunhofer Institute of Toxicology and Experimental Medicine (ITEM), Hannover, Germany.
Maximilian FuchsFraunhofer Institute of Toxicology and Experimental Medicine (ITEM), Hannover, Germany.
Annette JustInstitute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.
Andreas PichInstitute of Toxicology and Core Unit Proteomics, Hannover Medical School, Hannover, Germany.
Filippo PerbelliniInstitute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.
Christopher WerleinInstitute of Pathology, Hannover Medical School, Hannover, Germany.
Fabio IusDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.ORCID 0000-0002-8084-3360
Arjang RuhparwarDepartment of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.
Jan FiedlerFraunhofer Institute of Toxicology and Experimental Medicine (ITEM), Hannover, Germany.
Natalie WeberInstitute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.ORCID 0000-0002-2302-1045
Thomas ThumInstitute of Molecular and Translational Therapeutic Strategies (IMTTS), Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.ORCID 0000-0003-4360-1511
Medizinische Hochschule Hannover · DEFraunhofer Institute for Toxicology and Experimental Medicine · DE

Funding

ERC SFB1470
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Heart FailureMicroRNAsHumansMyocardiumMicroRNAsMIRN21 microRNA, human

Identifiers

PMID38442291
PMCPMC11156487
OpenAlexW4392444831

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.