Evidence map›Paper›PMID 38442242›Full record

ArticleACS chemical biology2024

Bioorthogonal Metabolic Labeling of the Virulence Factor Phenolic Glycolipid in Mycobacteria.

Lindsay E Guzmán, C J Cambier, Tan-Yun Cheng, Kubra F Naqvi, Michael U Shiloh, D Branch Moody, Carolyn R Bertozzi

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS chemical biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Biocompatible Chemistry: A Plug-and-Play Toolbox for Chemical Biology Research.Chembiochem : a European journal of chemical biology · 2025
    Review
  5. Review
  6. Journal of bacteriology · 2025
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Lindsay E GuzmánStanford Sarafan ChEM-H, Stanford University, Stanford, California 94305, United States.
C J CambierStanford Sarafan ChEM-H, Stanford University, Stanford, California 94305, United States.
Tan-Yun ChengBrigham and Women's Hospital, Division of Rheumatology, Inflammation and Immunity, Harvard Medical School, Boston, Massachusetts 02115, United States.
Kubra F NaqviDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States.ORCID 0000-0003-4703-9466
Michael U ShilohDepartment of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390, United States.
D Branch MoodyBrigham and Women's Hospital, Division of Rheumatology, Inflammation and Immunity, Harvard Medical School, Boston, Massachusetts 02115, United States.
Carolyn R BertozziStanford Sarafan ChEM-H, Stanford University, Stanford, California 94305, United States.ORCID 0000-0003-4482-2754
Stanford University · USBrigham and Women's Hospital · USThe University of Texas Southwestern Medical Center · US

Funding

Transmission Aerobiology of M. tuberculosis: Genes and Metabolic Pathways That Sustain Mtb Across an Evolutionary BottleneckP01AI159402 · NIAID · WEILL MEDICAL COLL OF CORNELL UNIV · PI BOUROUIBA, LYDIA · 2021 to 2025
$15.8M
T cell response to CDI-restricted lipids in tuberculosisR01AI049313 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI MOODY, DAVID BRANCH · 2001 to 2025
$10.6M
Mycobacterial Sulfation PathwaysR01AI051622 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI BERTOZZI, CAROLYN · 2002 to 2015
$6.0M
Chemical MycobateriologyR37AI051622 · NIAID · STANFORD UNIVERSITY · PI BERTOZZI, CAROLYN · 2016 to 2025
$4.7M
Mechanisms of cough in Mycobacterium tuberculosis transmissionR01AI158688 · NIAID · UT SOUTHWESTERN MEDICAL CENTER · PI SHILOH, MICHAEL · 2021 to 2025
$3.6M
Chemical Biological Discovery of Lipid Virulence Factors in the Major Bacterial PathogensR01AI165573 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI MOODY, DAVID BRANCH · 2022 to 2025
$3.0M
500 MHz NMR Spectrometer System with High Sensitivity Cryoprobe and Automated Sample Changer for Biochemical ResearchS10OD028697 · OD · STANFORD UNIVERSITY · PI BURNS, NOAH ZACHARY · 2020 to 2020
$709k
NIAID NIH HHS P01 AI159402NIAID NIH HHS R01 AI049313NIAID NIH HHS R01 AI051622NIAID NIH HHS R01 AI158688NIAID NIH HHS R01 AI165573NIAID NIH HHS R37 AI051622NIH HHS S10 OD028697
6 · The paper itself

Abstract

Surface lipids on pathogenic mycobacteria modulate infection outcomes by regulating host immune responses. Phenolic glycolipid (PGL) is a host-modulating surface lipid that varies among clinical

Indexed as

Mycobacterium marinumMycobacterium tuberculosisAnimalsGlycolipidsVirulence FactorsZebrafishGlycolipidsVirulence Factors

Identifiers

PMID38442242
PMCPMC10949201
OpenAlexW4392449018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.