Evidence map›Paper›PMID 38442081›Full record

ArticleAnnals of the New York Academy of Sciences2024

Expression of bond-related behaviors affects titi monkey responsiveness to oxytocin and vasopressin treatments.

Lynea R Witczak, Jaclyn Samra, Madison Dufek, Leana R Goetze, Sara M Freeman, Allison R Lau, Emily S Rothwell, Logan E Savidge, Rocío Arias-Del Razo, Alexander Baxter and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of the New York Academy of Sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Lynea R WitczakDepartment of Psychology, University of California, Davis, Davis, California, USA.ORCID 0000-0002-7265-6856
Jaclyn SamraDepartment of Psychology, University of California, Davis, Davis, California, USA.
Madison DufekCalifornia National Primate Research Center, University of California, Davis, Davis, California, USA.
Leana R GoetzeCalifornia National Primate Research Center, University of California, Davis, Davis, California, USA.
Sara M FreemanCalifornia National Primate Research Center, University of California, Davis, Davis, California, USA.
Allison R LauCalifornia National Primate Research Center, University of California, Davis, Davis, California, USA.
Emily S RothwellCalifornia National Primate Research Center, University of California, Davis, Davis, California, USA.
Logan E SavidgeDepartment of Psychology, University of California, Davis, Davis, California, USA.
Rocío Arias-Del RazoDepartment of Psychology, University of California, Davis, Davis, California, USA.
Alexander BaxterDepartment of Psychology, University of California, Davis, Davis, California, USA.
Chloe L KaraskiewiczDepartment of Psychology, University of California, Davis, Davis, California, USA.
Emilio FerrerDepartment of Psychology, University of California, Davis, Davis, California, USA.
Karen L BalesDepartment of Psychology, University of California, Davis, Davis, California, USA.ORCID 0000-0001-5826-2095
University of California, Davis · USUtah State University · US

Funding

National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
THE NEURAL BASIS OF PAIR-BONDING IN FEMALE TITI MONKEYSR01HD092055 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI BALES, KAREN L. · 2017 to 2021
$2.8M
NICHD NIH HHS R01 HD092055NIH HHS OD011107NIH HHS P51 OD011107
6 · The paper itself

Abstract

Social bonds influence physiology and behavior, which can shape how individuals respond to physical and affective challenges. Coppery titi monkey (Plecturocebus cupreus) offspring form selective bonds with their fathers, making them ideal for investigating how father-daughter bonds influence juveniles' responses to oxytocin (OT) and arginine-vasopressin (AVP) manipulations. We quantified the expression of father-daughter bond-related behaviors in females (n = 10) and gave acute intranasal treatments of saline, low/medium/high OT, low/high AVP, or an OT receptor antagonist (OTA) to subjects prior to a parent preference test. While females spent more time in proximity to their parents than strangers, we found a large degree of individual variation. Females with greater expression of bonding behaviors responded to OT treatments in a dose-dependent manner. Subjects also spent less time in proximity to strangers when treated with High OT (p = 0.003) and Low OT (p = 0.007), but more time when treated with High AVP (p = 0.007), Low AVP (p = 0.009), and OTA (p = 0.001). Findings from the present study suggest that variation in the expression of bond-related behaviors may alter responsiveness to OT and AVP, increasing engagement with unfamiliar social others. This enhanced sociality with strangers may promote the formation of pair bonds with partners.

Indexed as

CallicebusOxytocinAnimalsArginine VasopressinFemaleHumansSocial BehaviorVasopressinsArginine VasopressinOxytocinVasopressinsearly‐life experienceintranasal oxytocinintranasal vasopressinnonhuman primatepreference testproximity maintenancesocial bond

Identifiers

PMID38442081
PMCPMC11830493
OpenAlexW4392452494

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.