Evidence map›Paper›PMID 38442003›Full record

ArticleMicrobiology spectrum2024

Divergent mitochondrial responses and metabolic signal pathways secure the azole resistance in Crabtree-positive and negative

Meng Zhou, Jingwen Peng, Kun Ren, Yu Yu, Dongmei Li, Xiaodong She, Weida Liu

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Potential Strategies Applied byPathogens (Basel, Switzerland) · 2025
    Article
  7. Deciphering cargo contents in extracellular vesicles ofComputational and structural biotechnology journal · 2025
    Article
  8. Review
  9. Exploration of novel mechanisms of azole resistance inAntimicrobial agents and chemotherapy · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Meng ZhouDepartment of Medical Mycology, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.ORCID 0000-0001-5664-3871
Jingwen PengDepartment of Critical Care Medicine, Nanjing Jinling Hospital, Affiliated Hospital of Medicine School, Nanjing University, Nanjing, China.
Kun RenCenters for pharmaceutical preparations, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.
Yu YuDepartment of Medical Mycology, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.
Dongmei LiDepartment of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC, USA.ORCID 0000-0002-3272-2513
Xiaodong SheDepartment of Medical Mycology, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.ORCID 0000-0002-8719-0462
Weida LiuDepartment of Medical Mycology, Institute of Dermatology, Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNGeorgetown University · USNanjing General Hospital of Nanjing Military Command · CN

Funding

MOST | National Key Research and Development Program of China (NKPs) 2022YFC3601800MOST | National Natural Science Foundation of China (NSFC) 81972949MOST | National Natural Science Foundation of China (NSFC) 82304040
6 · The paper itself

Abstract

Azole drugs are the main therapeutic drugs for invasive fungal infections. However, azole-resistant strains appear repeatedly in the environment, posing a major threat to human health. Several reports have shown that mitochondria are associated with the virulence of pathogenic fungi. However, there are few studies on the mechanisms of mitochondria-mediated azoles resistance. Here, we first performed mitochondrial proteomic analysis on multiple

Indexed as

CandidaInvasive Fungal InfectionsAntifungal AgentsAzolesCandida albicansDrug Resistance, FungalHumansMicrobial Sensitivity TestsMitochondriaMitochondrial ProteinsProteomicsSignal TransductionAntifungal AgentsAzolesMitochondrial Proteinsazoles resistanceCandida speciesmitochondriaproteome

Identifiers

PMID38442003
PMCPMC10986575
OpenAlexW4392453736

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.