Evidence map›Paper›PMID 38441912›Full record

ArticleGlobal health action2024

"Arming half-baked people with weapons!" Information enclaving among professionals and the need for a care-centred model for antibiotic use information in Uganda, Tanzania and Malawi.

Susan Nayiga, Eleanor E MacPherson, John Mankhomwa, Fortunata Nasuwa, Raymond Pongolani, Rita Kabuleta, Mike Kesby, Russell Dacombe, Shona Hilton, Delia Grace and 2 more

Abstract read
In one paragraph

Article in Global health action, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Susan NayigaInfectious Diseases Research Collaboration, Kampala, Uganda.ORCID 0000-0002-1895-4035
Eleanor E MacPhersonResearch and Innovation Services, University of Glasgow, Glasgow, UK.ORCID 0000-0002-7142-1158
John MankhomwaMalawi-Liverpool-Wellcome Research Programme, Blantyre, Malawi.ORCID 0009-0001-1017-0471
Fortunata NasuwaKilimanjaro Clinical Research Institute (KCRI), Moshi, Tanzania.ORCID 0000-0003-4030-6154
Raymond PongolaniMalawi-Liverpool-Wellcome Research Programme, Blantyre, Malawi.ORCID 0000-0003-3145-5836
Rita KabuletaInfectious Diseases Research Collaboration, Kampala, Uganda.
Mike KesbySchool of Geography & Sustainable Development, University of St Andrews, St Andrews, UK.ORCID 0000-0001-7789-870X
Russell DacombeResearch and Innovation Services, University of Glasgow, Glasgow, UK.ORCID 0000-0002-6705-1537
Shona HiltonMRC/CSO Social and Public Health Sciences Unit, University of Glasgow, Glasgow, UK.ORCID 0000-0003-0633-8152
Delia GraceNatural Resources Institute, University of Greenwich, Chatham, UK.ORCID 0000-0002-0195-9489
Nicholas FeaseyMalawi-Liverpool-Wellcome Research Programme, Blantyre, Malawi.ORCID 0000-0003-4041-1405
Clare I R ChandlerDepartment of Global Health and Development, London School of Hygiene & Tropical Medicine, London, UK.ORCID 0000-0001-6499-7522

Funding

Medical Research Council MR/S004793/1Medical Research Council UK MR/S004785/1Medical Research Council UK MR/S004815/1
6 · The paper itself

Abstract

backgroundThe overuse of antimicrobial medicines is a global health concern, including as a major driver of antimicrobial resistance. In many low- and middle-income countries, a substantial proportion of antibiotics are purchased over-the-counter without a prescription. But while antibiotics are widely available, information on when and how to use them is not.

objectiveWe aimed to understand the acceptability among experts and professionals of sharing information on antibiotic use with end users - patients, carers and farmers - in Uganda, Tanzania and Malawi.

methodsBuilding on extended periods of fieldwork amongst end-users and antibiotic providers in the three countries, we conducted two workshops in each, with a total of 44 medical and veterinary professionals, policy makers and drug regulators, in December 2021. We carried out extensive documentary and literature reviews to characterise antibiotic information systems in each setting.

resultsParticipants reported that the general public had been provided information on medicine use in all three countries by national drug authorities, health care providers and in package inserts. Participants expressed concern over the danger of sharing detailed information on antibiotic use, particularly that end-users are not equipped to determine appropriate use of medicines. Sharing of general instructions to encourage professionally-prescribed practices was preferred.

conclusionsWithout good access to prescribers, the tension between enclaving and sharing of knowledge presents an equity issue. Transitioning to a client care-centred model that begins with the needs of the patient, carer or farmer will require sharing unbiased antibiotic information at the point of care.

Indexed as

Administrative PersonnelAnti-Bacterial AgentsHumansMalawiTanzaniaUgandaAnti-Bacterial AgentsAntimicrobial resistancedrug regulatorsenclaving of knowledgefarmersmedical knowledgemedical professionalspatientspolicy makersveterinary professionals

Identifiers

PMID38441912
PMCPMC10916894

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.