Evidence map›Paper›PMID 38441778›Full record

ArticleDrugs & aging2024

Management of Scleritis in Older Adults.

Laura Butler, Oren Tomkins-Netzer, Or Reiser, Rachael L Niederer

Open access · hybridAbstract read
In one paragraph

Article in Drugs & aging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Laura ButlerDepartment of Ophthalmology, University of Auckland, 85 Park Road, Grafton, Auckland, 1023, New Zealand.
Oren Tomkins-NetzerDepartment of Ophthalmology, Lady Davis Carmel Medical Centre, Haifa, Israel.
Or ReiserDepartment of Ophthalmology, Lady Davis Carmel Medical Centre, Haifa, Israel.
Rachael L NiedererDepartment of Ophthalmology, University of Auckland, 85 Park Road, Grafton, Auckland, 1023, New Zealand. r.niederer@auckland.ac.nz.ORCID 0000-0002-4311-859X
University of Auckland · NZCarmel Medical Center · ILTechnion – Israel Institute of Technology · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Scleritis, an inflammatory disease of the eye affecting scleral tissue, presents unique challenges in the older adult population. Unlike their younger counterparts, older individuals manifest a distinct spectrum of the disease with different underlying etiologies, co-morbidities, altered immune function, and an increased risk of systemic side effects from medication choices. Addressing these complexities necessitates a comprehensive and multidisciplinary approach. Treatment of choice will depend on any underlying cause but generally involves non-steroidal anti-inflammatory drugs, systemic or local corticosteroids, and potentially disease-modifying anti-rheumatic drugs. Utilization of these therapeutic agents in older adults warrants careful consideration because of their potential side-effect profiles. This article critically examines the specific concerns for the use of these drugs in older patients and reviews the existing literature on their use in this specific cohort.

Indexed as

ScleritisAdrenal Cortex HormonesAgedAnti-Inflammatory Agents, Non-SteroidalHumansImmunosuppressive AgentsTreatment OutcomeAdrenal Cortex HormonesAnti-Inflammatory Agents, Non-SteroidalImmunosuppressive Agents

Identifiers

PMID38441778
PMCPMC11021297
OpenAlexW4392464853

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.