Evidence map›Paper›PMID 38441718›Full record

ArticleAging clinical and experimental research2024

Prognostic nutritional index during hospitalization correlates with adverse outcomes in elderly patients with acute myocardial infarction: a single-center retrospective cohort study.

Mingxuan Li, Jiasheng Cai, Kewei Jiang, Yanglei Li, Siqi Li, Qingyue Wang, Haibo Liu, Xinkai Qu, Chengqi Kong, Kailei Shi

Open access · hybridAbstract read
In one paragraph

Article in Aging clinical and experimental research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Mingxuan Li *Department of Cardiology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Jiasheng Cai *Department of Cardiology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Kewei Jiang *Department of Respiratory Medicine, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Yanglei LiDepartment of Cardiology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Siqi LiDepartment of Cardiology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Qingyue WangDepartment of Cardiology, Huadong Hospital Affiliated to Fudan University, Shanghai, China.
Haibo LiuDepartment of Cardiology, Qingpu Branch of Zhongshan Hospital Affiliated to Fudan University, Shanghai, China. haiboliu13@fudan.edu.cn.
Xinkai QuDepartment of Cardiology, Huadong Hospital Affiliated to Fudan University, Shanghai, China. qxkchest@126.com.
Chengqi KongDepartment of Cardiology, Huadong Hospital Affiliated to Fudan University, Shanghai, China. chengqikong@163.com.
Kailei ShiDepartment of Cardiology, Huadong Hospital Affiliated to Fudan University, Shanghai, China. shikailei@fudan.edu.cn.ORCID http://orcid.org/0009-0008-2885-8224
Fudan University · CN

Funding

National Key Research and Development Program of China 2020YFC2009001the Science and Technology Commission of Shanghai Municipality 22ZR1422000
6 · The paper itself

Abstract

BACKGROUND AND

aimsAcute myocardial infarction (AMI) is one of the most prevalent illnesses endangering the elderly's health. The predictive nutritional index (PNI) has been shown in several studies to be a good predictor of nutritional prognosis. In this study, we explored the correlation between PNI during hospitalization and the outcome of elderly AMI patients.

methodsElderly AMI patients in the Cardiac Intensive Care Unit of Huadong Hospital from September 2017 to April 2020 were recruited for analysis. The clinical and laboratory examination data of subjects were retrieved. All enrolled patients were monitored following discharge. The primary clinical endpoints encompass major adverse cardiovascular events (MACEs) and Composite endpoint (MACEs and all-cause mortality). Survival analyses were conducted via the Kaplan-Meier and the log-rank analyses, and the Cox, proportional hazards model, was employed for hazard rate (HR) calculation.

results307 subjects were recruited for analysis. The optimal PNI threshold is 40.923. Based on the Kaplan-Meier analysis, the elevated PNI group experienced better prognosis (P < 0.001). Cox analysis demonstrated that the PNI group was a stand-alone predictor for elderly AMI patient prognosis (HR = 1.674, 95% CI 1.076-2.604, P = 0.022). Subgroup analysis showed that the HR of the PNI group was the highest in the ST-segment elevation myocardial infarction (STEMI) subgroup (HR = 3.345, 95% CI 1.889-5.923, P = 0.05), but no discernible difference was observed in the non-ST-segment elevation myocardial infarction (NSTEMI) subgroup.

conclusionBased on our analyses, the PNI during hospitalization can accurately predict the prognosis of elderly STEMI patients but not that of elderly NSTEMI patients.

Indexed as

Myocardial InfarctionNon-ST Elevated Myocardial InfarctionST Elevation Myocardial InfarctionAgedHospitalizationHumansNutrition AssessmentPrognosisRetrospective StudiesAcute myocardial infarctionElderlyPrognosisPrognostic nutritional index

Identifiers

PMID38441718
PMCPMC10914925
OpenAlexW4392456531

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LicenceCC BY
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.