Evidence map›Paper›PMID 38441609›Full record

ArticleJournal of neurology2024

Evaluation of a self-administered iPad

Stefanie Hechenberger, Birgit Helmlinger, Christian Tinauer, Emanuel Jauk, Stefan Ropele, Bettina Heschl, Sebastian Wurth, Anna Damulina, Sebastian Eppinger, Rina Demjaha and 3 more

Abstract read
In one paragraph

Article in Journal of neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Plateau of practice effects and noise with repeat SDMT testing in multiple sclerosis.Multiple sclerosis (Houndmills, Basingstoke, England) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Stefanie HechenbergerResearch Unit for Neuronal Plasticity and Repair, Medical University of Graz, Graz, Austria.ORCID http://orcid.org/0000-0002-2839-4000
Birgit HelmlingerResearch Unit for Neuronal Plasticity and Repair, Medical University of Graz, Graz, Austria.ORCID http://orcid.org/0000-0001-5022-2910
Christian TinauerDepartment of Neurology, Medical University of Graz, Graz, Austria.ORCID http://orcid.org/0000-0003-4355-3898
Emanuel JaukDepartment of Medical Psychology, Psychosomatics, and Psychotherapy, Medical University of Graz, Graz, Austria.ORCID http://orcid.org/0000-0003-3267-1688
Stefan RopeleDepartment of Neurology, Medical University of Graz, Graz, Austria.ORCID http://orcid.org/0000-0002-5559-768X
Bettina HeschlDepartment of Neurology, Medical University of Graz, Graz, Austria.
Sebastian WurthDepartment of Neurology, Medical University of Graz, Graz, Austria.ORCID http://orcid.org/0000-0001-7122-0842
Anna DamulinaDepartment of Neurology, Medical University of Graz, Graz, Austria.ORCID http://orcid.org/0000-0001-8241-2727
Sebastian EppingerDepartment of Neurology, Medical University of Graz, Graz, Austria.
Rina DemjahaDepartment of Neurology, Medical University of Graz, Graz, Austria.ORCID http://orcid.org/0000-0001-9725-9809
Michael KhalilDepartment of Neurology, Medical University of Graz, Graz, Austria.ORCID http://orcid.org/0000-0002-5350-3328
Christian EnzingerResearch Unit for Neuronal Plasticity and Repair, Medical University of Graz, Graz, Austria.ORCID http://orcid.org/0000-0001-9764-7617
Daniela PinterResearch Unit for Neuronal Plasticity and Repair, Medical University of Graz, Graz, Austria. daniela.pinter@medunigraz.at.ORCID http://orcid.org/0000-0003-3138-5225

Funding

Biogen AT-MSG-11729
6 · The paper itself

Abstract

backgroundLimited resources often hinder regular cognitive assessment of people with multiple sclerosis (pwMS) in standard clinical care. A self-administered iPad®-based cognitive screening-tool (Processing Speed Test; PST) might mitigate this problem.

objectiveTo evaluate the PST in clinical routine.

methodsWe investigated the feasibility of the PST in both a quiet and a waiting room setting. We assessed the validity of the PST in comparison with the established Symbol Digit Modalities Test (SDMT). We explored associations between processing speed assessments and the Brief International Cognitive Assessment for MS (BICAMS), magnetic resonance imaging (MRI) parameters, and psychological factors. Additionally, we explored the ability of the PST to detect impairment in processing speed compared to the SDMT.

resultsThe PST was feasible in the waiting room setting. PST and SDMT correlated comparably with the BICAMS, MRI parameters, and psychological variables. Of 172 pwMS, 50 (30.8%) showed cognitive impairment according to the BICAMS; respective values were 47 (27.3%) for the SDMT and 9 (5.2%) for the PST.

conclusionsThe PST performed in a waiting room setting correlates strongly with established cognitive tests. It thus may be used to assess processing speed in a resource-efficient manner and complement cognitive assessment in clinical routine. Despite comparable validity of the PST and SDMT, we identified more pwMS with impaired processing speed using normative data of the SDMT compared to the PST and advise caution, that the common cut-off score of - 1.5 SD from the current PST is not appropriate in Europe.

Indexed as

Cognitive DysfunctionComputers, HandheldMultiple SclerosisNeuropsychological TestsAdultAgedFeasibility StudiesFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedProcessing SpeedCognitionCognitive assessmentiPad®-based testMRIMultiple sclerosisProcessing speed

Identifiers

PMID38441609
PMCPMC11136781

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.