Evidence map›Paper›PMID 38441601›Full record

Trial reportArchives of gynecology and obstetrics2024

Comparison of DNA damage in granulosa cells of women undergoing controlled ovarian stimulation in in vitro fertilization protocols with the recombinant human follicle-stimulating hormones Corneumon

Ximena Alcalá-Sánchez, Pedro Cuapio-Padilla, Carlos Salazar-López, Ricardo Rodríguez, Mario Teteltitla, Iván Bahena, Miguel Betancourt, Eduardo Casas, Fahiel Casillas, Alma López and 1 more

Abstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in Archives of gynecology and obstetrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Ximena Alcalá-Sánchez *Department of Health Sciences, Metropolitan Autonomous University-Iztapalapa Campus, 09340, Mexico City, Mexico.
Pedro Cuapio-Padilla *HISPAREP Assisted Reproduction Clinic, Hospital Español, 11520 CDMX, Mexico City, Mexico.
Carlos Salazar-LópezHISPAREP Assisted Reproduction Clinic, Hospital Español, 11520 CDMX, Mexico City, Mexico.
Ricardo RodríguezHISPAREP Assisted Reproduction Clinic, Hospital Español, 11520 CDMX, Mexico City, Mexico.
Mario TeteltitlaDepartment of Health Sciences, Metropolitan Autonomous University-Iztapalapa Campus, 09340, Mexico City, Mexico.
Iván BahenaDepartment of Health Sciences, Metropolitan Autonomous University-Iztapalapa Campus, 09340, Mexico City, Mexico.ORCID http://orcid.org/0000-0002-1361-3573
Miguel BetancourtDepartment of Health Sciences, Metropolitan Autonomous University-Iztapalapa Campus, 09340, Mexico City, Mexico.ORCID http://orcid.org/0000-0002-6427-4444
Eduardo CasasDepartment of Health Sciences, Metropolitan Autonomous University-Iztapalapa Campus, 09340, Mexico City, Mexico.ORCID http://orcid.org/0000-0001-7909-2806
Fahiel CasillasDepartment of Biology of Reproduction, Metropolitan Autonomous University-Iztapalapa Campus, 09340, Mexico City, Mexico.ORCID http://orcid.org/0000-0002-9916-0586
Alma LópezDepartment of Health Sciences, Metropolitan Autonomous University-Iztapalapa Campus, 09340, Mexico City, Mexico.
Edmundo BonillaDepartment of Health Sciences, Metropolitan Autonomous University-Iztapalapa Campus, 09340, Mexico City, Mexico. mundo@xanum.uam.mx.ORCID http://orcid.org/0000-0002-7939-4633
Universidad Autónoma Metropolitana · MXHospital Español · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo compare the DNA damage in granulosa cells (GCs) of women undergoing ovarian-stimulated cycles with four widely used recombinant human follicle-stimulating hormones (rhFSH) in in vitro fertilization (IVF) protocols (Corneumon

methodsA randomized trial was carried out at a Mexican hospital. GCs were isolated from 18 women with infertility undergoing assisted reproductive techniques (ART). Four controlled ovarian stimulation (COS) protocols including Corneumon

resultsUse of the different hrFSH in COS caused variable and statistically significant levels of DNA damage in GCs of infertile women. CTL was similar in the Corneumon

conclusionUse of Corneumon

Indexed as

Infertility, FemaleLuteinizing HormoneDNA DamageDrug CombinationsFemaleFertilization in VitroFollicle Stimulating HormoneFollicle Stimulating Hormone, HumanGranulosa CellsHumansOvulation InductionRecombinant ProteinsDrug CombinationsFollicle Stimulating HormoneFollicle Stimulating Hormone, Humanfollitropin alfafollitropin betaLuteinizing HormonepergoverisRecombinant ProteinsARTComet assayControlled ovarian stimulationGCsrhFSH

Identifiers

PMID38441601
OpenAlexW4392489324

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.