Evidence map›Paper›PMID 38441532›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2024

NUDC is critical for rod photoreceptor function, maintenance, and survival.

Mary Anne Garner, Meredith G Hubbard, Evan R Boitet, Seth T Hubbard, Anushree Gade, Guoxin Ying, Bryan W Jones, Wolfgang Baehr, Alecia K Gross

Open access · hybridAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. A mutation inMolecular vision · 2026
    Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mary Anne GarnerDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Meredith G HubbardDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Evan R BoitetDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Seth T HubbardDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Anushree GadeDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.
Guoxin YingDepartment of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah, USA.
Bryan W JonesDepartment of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0001-5527-6643
Wolfgang BaehrDepartment of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah, USA.ORCID 0000-0001-5003-9550
Alecia K GrossDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, Alabama, USA.ORCID 0000-0003-1857-6633
University of Alabama at Birmingham · USUniversity of Utah · US

Funding

Visual Phenotyping CoreP30EY003039 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LAWRENCE C SINCICH · 1985 to 2026
$16.9M
University of Utah, Core Vision Research GrantP30EY014800 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI PAUL STEVEN BERNSTEIN · 2005 to 2026
$14.6M
Retinal CircuitryR01EY028927 · NEI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Bryan William Jones · 2019 to 2026
$5.2M
Membrane Protein Transport in PhotoreceptorsR01EY019298 · NEI · UNIVERSITY OF UTAH · PI BAEHR, WOLFGANG · 2009 to 2018
$3.7M
Rhodopsin Trafficking and Retinal DegenerationsR01EY019311 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GROSS, ALECIA K · 2008 to 2012
$1.9M
Photoreceptor Disk Formation and Retinal DegenerationsR01EY030096 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GROSS, ALECIA K · 2020 to 2023
$1.8M
NEI NIH HHS P30 EY003039NEI NIH HHS P30 EY014800NEI NIH HHS R01 EY019298NEI NIH HHS R01 EY019311NEI NIH HHS R01 EY028927NEI NIH HHS R01 EY030096
6 · The paper itself

Abstract

NUDC (nuclear distribution protein C) is a mitotic protein involved in nuclear migration and cytokinesis across species. Considered a cytoplasmic dynein (henceforth dynein) cofactor, NUDC was shown to associate with the dynein motor complex during neuronal migration. NUDC is also expressed in postmitotic vertebrate rod photoreceptors where its function is unknown. Here, we examined the role of NUDC in postmitotic rod photoreceptors by studying the consequences of a conditional NUDC knockout in mouse rods (rNudC

Indexed as

ActinsDyneinsAnimalsBiological TransportCell Cycle ProteinsCell DeathMiceNuclear ProteinsRetinal Rod Photoreceptor CellsActinsCell Cycle ProteinsDyneinsNuclear ProteinsNudc protein, mouseactincofilin1dyneinNUDCphosphorylated cofilinphotoreceptorretinal degeneration

Identifiers

PMID38441532
PMCPMC10917122
OpenAlexW4392474046

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.