Evidence map›Paper›PMID 38441500›Full record

ArticleJournal of cell science2024

Perspectives on polarity - exploring biological asymmetry across scales.

Marieke Margaretha Glazenburg, Nynke Marije Hettema, Liedewij Laan, Ophélie Remy, Géraldine Laloux, Thibaut Brunet, Xin Chen, Yee Han Tee, Wenyu Wen, Mohd Suhail Rizvi and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cell science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Marieke Margaretha GlazenburgDepartment of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Delft, 2629 HZ, The Netherlands.ORCID 0000-0003-2586-641X
Nynke Marije HettemaDepartment of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Delft, 2629 HZ, The Netherlands.ORCID 0000-0003-1592-1710
Liedewij LaanDepartment of Bionanoscience, Kavli Institute of Nanoscience Delft, Delft University of Technology, Delft, 2629 HZ, The Netherlands.ORCID 0000-0002-7138-9004
Ophélie RemyInstitut de Duve, UCLouvain, 75 avenue Hippocrate, 1200 Brussels, Belgium.ORCID 0000-0001-7255-7885
Géraldine LalouxInstitut de Duve, UCLouvain, 75 avenue Hippocrate, 1200 Brussels, Belgium.ORCID 0000-0003-3230-1679
Thibaut BrunetInstitut Pasteur, Université Paris-Cité, CNRS UMR 3691, Evolutionary Cell Biology and Evolution of Morphogenesis Unit, 25-28 rue du docteur Roux, 75015 Paris, France.ORCID 0000-0002-1843-1613
Xin ChenHoward Hughes Medical Institute and Department of Biology, Johns Hopkins University, Levi Hall 137, 3400 North Charles Street, Baltimore, MD 21218-2685, USA.ORCID 0000-0002-6990-0926
Yee Han TeeMechanobiology Institute, National University of Singapore, Singapore 117411, Singapore.ORCID 0000-0001-9779-0915
Wenyu WenDepartment of Neurosurgery, Huashan Hospital, State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, Institutes of Biomedical Sciences, School of Basic Medical Sciences, Fudan University, Shanghai 200032, China.ORCID 0000-0002-0798-4730
Mohd Suhail RizviDepartment of Biomedical Engineering, Indian Institute of Technology Hyderabad, Sangareddy 502284, India.ORCID 0000-0002-4130-4671
Mohit Kumar JollyDepartment of Bioengineering, Indian Institute of Science, Bangalore 560012, India.ORCID 0000-0002-6631-2109
Meghan RiddellDepartment of Physiology and Department of Obstetrics and Gynecology, University of Alberta, Edmonton, AB, T6G 2S2, Canada.ORCID 0000-0002-3203-2897

Funding

Study epigenetic inheritance during development, homeostasis and regenerationR35GM127075 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Xin Chen · 2018 to 2026
$3.2M
Epigenetic Regulation of Germ Cell Differentiation from a Stem Cell LineageR01HD102474 · NICHD · JOHNS HOPKINS UNIVERSITY · PI CHEN, XIN · 2020 to 2024
$1.7M
CIHREuropean Research CouncilHoward Hughes Medical InstituteNICHD NIH HHS R01 HD102474NIGMS NIH HHS R35 GM127075
6 · The paper itself

Abstract

In this Perspective, Journal of Cell Science invited researchers working on cell and tissue polarity to share their thoughts on unique, emerging or open questions relating to their field. The goal of this article is to feature 'voices' from scientists around the world and at various career stages, to bring attention to innovative and thought-provoking topics of interest to the cell biology community. These voices discuss intriguing questions that consider polarity across scales, evolution, development and disease. What can yeast and protists tell us about the evolution of cell and tissue polarity in animals? How are cell fate and development influenced by emerging dynamics in cell polarity? What can we learn from atypical and extreme polarity systems? How can we arrive at a more unified biophysical understanding of polarity? Taken together, these pieces demonstrate the broad relevance of the fascinating phenomenon of cell polarization to diverse fundamental biological questions.

Indexed as

Cell PolarityResearch PersonnelAnimalsBiophysicsCell DifferentiationHumansSaccharomyces cerevisiaeCell polarityEpitheliaEvolutionSelf-organizationTissue polarity

Identifiers

PMID38441500
PMCPMC11382653

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.