Evidence map›Paper›PMID 38441306›Full record

ArticleCancer reports (Hoboken, N.J.)2024

Nomograms to predict long-term survival for patients with gallbladder carcinoma after resection.

Shilei Bai, Pinghua Yang, Jiliang Qiu, Jie Wang, Liu Liu, Chunyan Wang, Huifeng Wang, Zhijian Wen, Baohua Zhang

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer reports (Hoboken, N.J.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Shilei BaiDepartment of Hepatic Surgery II, The Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, China.
Pinghua YangDepartment of Biliary Surgery IV, The Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, China.
Jiliang QiuDepartment of Hepatobiliary Surgery, Sun Yat-Sen University Cancer Center, Guangzhou, China.
Jie WangDepartment of Hepatic Surgery II, The Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, China.
Liu LiuDepartment of Hepatic Surgery II, The Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, China.
Chunyan WangDepartment of Hepatic Surgery II, The Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, China.
Huifeng WangDepartment of Hepatic Surgery, The Fifth Clinical Medical College of Henan University of Chinese Medicine.
Zhijian WenDepartment of Hepatobiliary Pancreatic Vascular Surgery, The Chenggong Hospital, Xiamen University, Xiamen, China.
Baohua ZhangDepartment of Biliary Surgery IV, The Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, China.ORCID 0000-0001-5970-3796
Second Military Medical University · CNFirst Affiliated Hospital of Henan University · CNSun Yat-sen University · CNXiamen University · CN

Funding

Natural Science Foundation of Shanghai Municipality 81372674The Project of Shanghai Shenkang Hospital Development Center SHDC12016127
6 · The paper itself

Abstract

backgroundSurgical resection remains the primary treatment option for gallbladder carcinoma (GBC). However, there is a pressing demand for prognostic tools that can refine patients' treatment choices and tailor personalized therapies accordingly.

aimsThe nomograms were constructed using the data of a training cohort (n = 378) of GBC patients at Eastern Hepatobiliary Surgery Hospital (EHBH) between 2008 and 2018. The model's performance was validated in GBC patients (n = 108) at Guangzhou Centre from 2007 to 2018. METHODS AND

resultsThe 5-year overall survival (OS) rate in the training cohort was 24.4%. Multivariate analyses were performed using preoperative and postoperative data to identify independent predictors of OS. These predictors were then incorporated into preoperative and postoperative nomograms, respectively. The C-index of the preoperative nomogram was 0.661 (95% CI, 0.627 to 0.694) for OS prediction and correctly delineated four subgroups (5-year OS rates: 48.1%, 19.0%, 15.6%, and 8.1%, p < 0.001). The C-index of the postoperative nomogram was 0.778 (95%CI, 0.756 -0.800). Furthermore, this nomogram was superior to the 8th TNM system in both C-index and the net benefit on decision curve analysis. The results were externally validated.

conclusionThe two nomograms showed an optimally prognostic prediction in GBC patients after curative-intent resection.

Indexed as

Gallbladder NeoplasmsNomogramsHumansPostoperative Perioddecision curve analysisgallbladder carcinomanomogramprognosisresectionTNM system

Identifiers

PMID38441306
PMCPMC10913079
OpenAlexW4392460058

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.