Evidence map›Paper›PMID 38441023›Full record

ReviewCurrent topics in medicinal chemistry2024

Ginsenoside Rg3: A Review of its Anticancer Mechanisms and Potential Therapeutic Applications.

Lei Wu, Lin Bai, Wenshu Dai, Yaping Wu, Pengjun Xi, Jie Zhang, Lily Zheng

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current topics in medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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  7. Exploring the molecular basis ofBioinformatics advances · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lei WuCore Facility of West China Hospital, Sichuan University, Chengdu, 610041, China.
Lin BaiCore Facility of West China Hospital, Sichuan University, Chengdu, 610041, China.
Wenshu DaiNHC Key Laboratory of Transplant Engineering and Immunology, Frontier Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Yaping WuCore Facility of West China Hospital, Sichuan University, Chengdu, 610041, China.
Pengjun XiDivision of Infectious Diseases, Department of Medicine Solna and Center for Molecular Medicine, Karolinska Institute, Stockholm, Sweden.
Jie ZhangCore Facility of West China Hospital, Sichuan University, Chengdu, 610041, China.
Lily ZhengTCM Regulating Metabolic Diseases Key Laboratory of Sichuan Province, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, 610075, Sichuan Province, China.

Funding

National Natural Science Foundation of China 82204951Sichuan Province Science and Technology Support Program 2020JDRC0102
6 · The paper itself

Abstract

backgroundTraditional Chinese Medicine (TCM) has a long history of treating various diseases and is increasingly being recognized as a complementary therapy for cancer. A promising natural compound extracted from the Chinese herb ginseng is ginsenoside Rg3, which has demonstrated significant anticancer effects. It has been tested in a variety of cancers and tumors and has proven to be effective in suppressing cancer.

objectivesThis work covers various aspects of the role of ginsenoside Rg3 in cancer treatment, including its biological functions, key pathways, epigenetics, and potential for combination therapies, all of which have been extensively researched and elucidated. The study aims to provide a reference for future research on ginsenoside Rg3 as an anticancer agent and a support for the potential application of ginsenoside Rg3 in cancer treatment.

Indexed as

GinsenosidesNeoplasmsAnimalsAntineoplastic AgentsAntineoplastic Agents, PhytogenicCell ProliferationHumansMedicine, Chinese TraditionalAntineoplastic AgentsAntineoplastic Agents, Phytogenicginsenoside Rg3GinsenosidesAnticancerCombination therapies.Epigenetic pathwaysGinsenoside Rg3Important cellular functionsImportant pathways

Identifiers

PMID38441023

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.