Evidence map›Paper›PMID 38440898›Full record

ReviewRegenerative medicine2024

The challenges and prospects of smooth muscle tissue engineering.

Christofer S Baldwin, Shilpa Iyer, Raj R Rao

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Regenerative medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Christofer S BaldwinDepartment of Biomedical Engineering, College of Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
Shilpa IyerDepartment of Biological Sciences, Fulbright College of Arts & Sciences, University of Arkansas, Fayetteville, AR 72701, USA.ORCID 0000-0001-6287-2232
Raj R RaoDepartment of Biomedical Engineering, College of Engineering, University of Arkansas, Fayetteville, AR 72701, USA.ORCID 0000-0003-0544-413X

Funding

Metabolic regulation of MODS in pediatric mitochondrial disordersR01HD110536 · NICHD · UNIVERSITY OF ARKANSAS AT FAYETTEVILLE · PI Shilpa Iyer · 2023 to 2026
$2.5M
NICHD NIH HHS R01 HD110536
6 · The paper itself

Abstract

Many vascular disorders arise as a result of dysfunctional smooth muscle cells. Tissue engineering strategies have evolved as key approaches to generate functional vascular smooth muscle cells for use in cell-based precision and personalized regenerative medicine approaches. This article highlights some of the challenges that exist in the field and presents some of the prospects for translating research advancements into therapeutic modalities. The article emphasizes the need for better developing synergetic intracellular and extracellular cues in the processes to generate functional vascular smooth muscle cells from different stem cell sources for use in tissue engineering strategies.

Indexed as

Muscle, SmoothTissue EngineeringMyocytes, Smooth MuscleRegenerative MedicineStem Cellsbiochemicalbiophysicalcardiovascularmitochondriaregenerative engineering • smooth musclesstem cellstissue engineering

Identifiers

PMID38440898
PMCPMC10941056

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.