ArticleJournal of geriatric cardiology : JGC2024
Multimorbidity and mortality among older patients with coronary heart disease in Shenzhen, China.
Article in Journal of geriatric cardiology : JGC, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Risk prediction models for mortality in patients with multimorbidity: a systematic review and meta-analysis.Frontiers in public health · 2025Pooled it
- Age at Coronary Heart Disease Onset, Genetic Susceptibility, and Subsequent Risk of Stroke.Journal of the American Heart Association · 2026Article
- Association of multimorbidity with mortality risk in Chinese senior adults: a population-based cohort study.BMC geriatrics · 2026Article
- Impact of prehospital triggers, time of onset, and symptom-to-door time on the prognosis of patients with coronary heart disease.Frontiers in public health · 2026Article
- Osteoporosis and risk of dementia among older adults: a population‑based cohort study.Bone research · 2025Observational
- The mediating role of physical activity self-efficacy between knowledge, psychological factors, and early physical activity in elderly post-PCI patients: a cross-sectional study.BMC geriatrics · 2025Article
- Long-term systolic blood pressure and cardiovascular risks among patients with ischemic stroke: a register-based cohort study.Journal of global health · 2025Article
- Prevalence of Multimorbidity in Lithuania: Insights from National Health Insurance Fund Data.Journal of cardiovascular development and disease · 2025Article
- Associations between multimorbidity and unintentional falls among older adults with coronary heart disease.Frontiers in public health · 2025Article
- An unsupervised cluster analysis of multimorbidity patterns in older adults in Shenzhen, China.Frontiers in public health · 2025Article
- Benzodiazepine use and incident risk of sudden cardiac arrest in patients with cardiovascular diseases.Science progressArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe current understanding of the magnitude and consequences of multimorbidity in Chinese older adults with coronary heart disease (CHD) is insufficient. We aimed to assess the association and population-attributable fractions (PAFs) between multimorbidity and mortality among hospitalized older patients who were diagnosed with CHD in Shenzhen, China.
methodsWe conducted a retrospective cohort study of older Chinese patients (aged ≥ 65 years) who were diagnosed with CHD. Cox proportional hazards models were used to estimate the associations between multimorbidity and all-cause and cardiovascular disease (CVD) mortality. We also calculated the PAFs.
resultsThe study comprised 76,455 older hospitalized patients who were diagnosed with CHD between January 1, 2016, and August 31, 2022. Among them, 70,217 (91.9%) had multimorbidity, defined as the presence of at least one of the predefined 14 chronic conditions. Those with cancer, hemorrhagic stroke and chronic liver disease had the worst overall death risk, with adjusted HRs (95% CIs) of 4.05 (3.77, 4.38), 2.22 (1.94, 2.53), and 1.85 (1.63, 2.11), respectively. For CVD mortality, the highest risk was observed for hemorrhagic stroke, ischemic stroke, and chronic kidney disease; the corresponding adjusted HRs (95% CIs) were 3.24 (2.77, 3.79), 1.91 (1.79, 2.04), and 1.81 (1.64, 1.99), respectively. All-cause mortality was mostly attributable to cancer, heart failure and ischemic stroke, with PAFs of 11.8, 10.2, and 9.1, respectively. As for CVD mortality, the leading PAFs were heart failure, ischemic stroke and diabetes; the corresponding PAFs were 18.0, 15.7, and 6.1, respectively.
conclusionsMultimorbidity was common and had a significant impact on mortality among older patients with CHD in Shenzhen, China. Cancer, heart failure, ischemic stroke and diabetes are the primary contributors to PAFs. Therefore, prioritizing improved treatment and management of these comorbidities is essential for the survival prognosis of CHD patients from a holistic public health perspective.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.