Evidence map›Paper›PMID 38440332›Full record

ArticlemicroPublication biology2024

The P granule antibody KT3 recognizes epitopes in both PGL-1 and PGL-3.

Brennan M Danlasky, Mario Martinez, Madeline Cassani, Devavrat Bodas, Andrea Putnam, Geraldine Seydoux

Abstract read
In one paragraph

Article in microPublication biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Brennan M DanlaskyMolecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine.
Mario MartinezMolecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine.
Madeline CassaniMolecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine.
Devavrat BodasMolecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine.
Andrea PutnamMolecular Biology and Genetics, University of Wisconsin-Madison, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine.
Geraldine SeydouxMolecular Biology and Genetics, Howard Hughes Medical Institute, Johns Hopkins University School of Medicine.

Funding

Regulation of Germ Cell Fate During EmbryogenesisR37HD037047 · NICHD · JOHNS HOPKINS UNIVERSITY · PI SEYDOUX, GERALDINE CATHERINE JOELLE · 2016 to 2025
$3.8M
Predoctoral Training Program in Human GeneticsT32GM148383 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI Kimberly F Doheny, ANDREW S MCCALLION · 2023 to 2026
$2.4M
NICHD NIH HHS R37 HD037047NIGMS NIH HHS T32 GM148383
6 · The paper itself

Abstract

The KT3 antibody is a commercially available antibody that recognizes the P granule protein PGL-3 (Takeda et al., 2008). Using immunostaining and western blotting of purified peptide fragments, we show that KT3 recognizes both PGL-3 and its paralog PGL-1 , likely through a shared epitope in the intrinsically disordered region.

Identifiers

PMID38440332
PMCPMC10910292

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.