Evidence map›Paper›PMID 38440067›Full record

ReviewFrontiers in neuroanatomy2024

Cajal, the neuronal theory and the idea of brain plasticity.

Jairo A Rozo, Irene Martínez-Gallego, Antonio Rodríguez-Moreno

Abstract readReview
In one paragraph

Review in Frontiers in neuroanatomy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Defining the electrical synapse.Nature reviews. Neuroscience · 2026
    Review
  2. Article
  3. Review
  4. Review
  5. Cajal the artist. The origins of a passion.Frontiers in neuroanatomy · 2026
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jairo A RozoLaboratory of Cellular Neuroscience and Plasticity, Universidad Pablo de Olavide, Seville, Spain.
Irene Martínez-GallegoLaboratory of Cellular Neuroscience and Plasticity, Universidad Pablo de Olavide, Seville, Spain.
Antonio Rodríguez-MorenoLaboratory of Cellular Neuroscience and Plasticity, Universidad Pablo de Olavide, Seville, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper reviews the importance of Cajal's neuronal theory (the Neuron Doctrine) and the origin and importance of the idea of brain plasticity that emerges from this theory. We first comment on the main Cajal's discoveries that gave rise and confirmed his Neuron Doctrine: the improvement of staining techniques, his approach to morphological laws, the concepts of dynamic polarisation, neurogenesis and neurotrophic theory, his first discoveries of the nerve cell as an independent cell, his research on degeneration and regeneration and his fight against reticularism. Second, we review Cajal's ideas on brain plasticity and the years in which they were published, to finally focus on the debate on the origin of the term plasticity and its conceptual meaning, and the originality of Cajal's proposal compared to those of other authors of the time.

Indexed as

historylegacyneuronal theoryplasticitySantiago Ramón y Cajal

Identifiers

PMID38440067
PMCPMC10910026

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.