Evidence map›Paper›PMID 38439804›Full record

ArticleEcancermedicalscience2024

The role of modern parameters and their relationship with recurrence risk as assessed by Oncotype DX: real-world evidence.

Dana Narvaez, Jorge Nadal, Adrian Nervo, Victoria Costanzo, Claudio Paletta, Fernando Petracci, Sergio Rivero, Alexis Ostinelli, Federico Coló, Loza Martín and 6 more

Open access · goldAbstract read
In one paragraph

Article in Ecancermedicalscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Dana NarvaezAlexander Fleming Institute, Buenos Aires 1425, Argentina.
Jorge NadalAlexander Fleming Institute, Buenos Aires 1425, Argentina.
Adrian NervoAlexander Fleming Institute, Buenos Aires 1425, Argentina.
Victoria CostanzoAlexander Fleming Institute, Buenos Aires 1425, Argentina.
Claudio PalettaAlexander Fleming Institute, Buenos Aires 1425, Argentina.
Fernando PetracciAlexander Fleming Institute, Buenos Aires 1425, Argentina.
Sergio RiveroAlexander Fleming Institute, Buenos Aires 1425, Argentina.
Alexis OstinelliAlexander Fleming Institute, Buenos Aires 1425, Argentina.
Federico ColóAlexander Fleming Institute, Buenos Aires 1425, Argentina.
Loza MartínAlexander Fleming Institute, Buenos Aires 1425, Argentina.
Veronica FabianoAlexander Fleming Institute, Buenos Aires 1425, Argentina.
Luciana SabatiniAlexander Fleming Institute, Buenos Aires 1425, Argentina.
Azul PerazzoloAlexander Fleming Institute, Buenos Aires 1425, Argentina.
Mora AmatAlexander Fleming Institute, Buenos Aires 1425, Argentina.
Matias ChaconAlexander Fleming Institute, Buenos Aires 1425, Argentina.
Federico WaisbergAlexander Fleming Institute, Buenos Aires 1425, Argentina.
Instituto Alexander Fleming · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genomic analysis through various platforms is an essential tool for determining prognosis and treatment in a significant subgroup of early-stage breast cancer patients with hormone receptor-positive and human epidermal growth factor receptor 2 (HER2)-negative status. Additionally, combined clinical and pathological characteristics can accurately predict the recurrence score (RS), as demonstrated by the University of Tennessee risk nomogram. In this study, we aimed to identify classical clinical-pathological factors associated with high RS in a local population, including modern parameters such as current abemaciclib treatment recommendations, HER2-low status, different Ki-67 cutoff values, and samples obtained from secondary primary tumours. This is a retrospective single-institution study that analysed a total of 215 tumour samples. Among lymph node-negative patients (

Indexed as

breast cancergenomic platformsrecurrence risksecond primary tumour

Identifiers

PMID38439804
PMCPMC10911664
OpenAlexW4391574920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.