Evidence map›Paper›PMID 38439020›Full record

SynthesisBMC oral health2024

Adhesion of Candida Albicans to digital versus conventional acrylic resins: a systematic review and meta-analysis.

Mohammed Nasser Alhajj, Esam Halboub, Norlela Yacob, Sadeq Ali Al-Maweri, Siti Fauzza Ahmad, Asja Celebić, Hesham M Al-Mekhlafi, Nosizana Mohd Salleh

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC oral health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Surface Changes Induced by Brushing IncreaseJournal of fungi (Basel, Switzerland) · 2025
    Article
  5. Article
  6. Exploring the role of candidalysin in the pathogenicity ofAmerican journal of translational research · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mohammed Nasser AlhajjDepartment of Restorative Dentistry, Faculty of Dentistry, Universiti Malaya, 50603, Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia.
Esam HalboubDepartment of Maxillofacial Surgery and Diagnostic Sciences, College of Dentistry, Jazan University, Jazan, Saudi Arabia.
Norlela YacobDepartment of Conservative Dentistry & Prosthodontics, Faculty of Dentistry, Universiti Sains Islam Malaysia, Negeri Sembilan, Malaysia.
Sadeq Ali Al-MaweriCollege of Dental Medicine, QU Health, Qatar University, Doha, Qatar.
Siti Fauzza AhmadDepartment of Restorative Dentistry, Faculty of Dentistry, Universiti Malaya, 50603, Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia.
Asja CelebićDepartment of Removable Prosthodontics, Faculty of Dentistry, University of Zagreb, Zagreb, Croatia.
Hesham M Al-MekhlafiDepartment of Parasitology, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia.
Nosizana Mohd SallehDepartment of Restorative Dentistry, Faculty of Dentistry, Universiti Malaya, 50603, Kuala Lumpur, Federal Territory of Kuala Lumpur, Malaysia. nosizana@um.edu.my.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe present systematic review and meta-analysis investigated the available evidence about the adherence of Candida Albicans to the digitally-fabricated acrylic resins (both milled and 3D-printed) compared to the conventional heat-polymerized acrylic resins.

methodsThis study followed the guidelines of the Preferred Reporting Items for Systematic Review and Meta-analyses (PRISMA). A comprehensive search of online databases/search tools (Web of Science, Scopus, PubMed, Ovid, and Google Scholar) was conducted for all relevant studies published up until May 29, 2023. Only in-vitro studies comparing the adherence of Candida albicans to the digital and conventional acrylic resins were included. The quantitative analyses were performed using RevMan v5.3 software.

resultsFourteen studies were included, 11 of which were meta-analyzed based on Colony Forming Unit (CFU) and Optical Density (OD) outcome measures. The pooled data revealed significantly lower candida colonization on the milled digitally-fabricated compared to the heat-polymerized conventionally-fabricated acrylic resin materials (MD = - 0.36; 95%CI = - 0.69, - 0.03; P = 0.03 and MD = - 0.04; 95%CI = - 0.06, - 0.01; P = 0.0008; as measured by CFU and OD respectively). However, no differences were found in the adhesion of Candida albicans between the 3D-printed digitally-fabricated compared to the heat-polymerized conventionally-fabricated acrylic resin materials (CFU: P = 0.11, and OD: P = 0.20).

conclusionThe available evidence suggests that candida is less likely to adhere to the milled digitally-fabricated acrylic resins compared to the conventional ones.

Indexed as

Acrylic ResinsCandida albicansDatabases, FactualAcrylic ResinsAcrylic resinCAD-CAMCandida AlbicansDigital dentureProsthodontics

Identifiers

PMID38439020
PMCPMC10910815

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.