Evidence map›Paper›PMID 38438996›Full record

ArticleBMC geriatrics2024

Development of a multidisciplinary medication management program in nursing homes: protocol for a randomized controlled trial : Multidisciplinary medication management in nursing homes.

Hye Jun Lee, Sunmee Jang, Ju-Yeun Lee, Young-Mi Ah, Mi-Kyung Lee, Suhyun Jang, Sena An, Jung-Ha Kim

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMC geriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 0 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Hye Jun LeeDepartment of Family Medicine, Chung-Ang University Hospital, College of Medicine, Chung-Ang University, Seoul, 06973, South Korea.
Sunmee JangCollege of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon, South Korea.
Ju-Yeun LeeCollege of Pharmacy and Research Institute of Pharmaceutical Sciences, Seoul National University, Seoul, South Korea.
Young-Mi AhCollege of Pharmacy, Yeungnam University, Gyeongsan, Gyeongbuk, South Korea.
Mi-Kyung LeeDepartment of Laboratory Medicine, Chung-Ang University Hospital, College of Medicine, Chung-Ang University, Seoul, South Korea.
Suhyun JangCollege of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, Incheon, South Korea.
Sena AnDepartment of Family Medicine, Chung-Ang University Hospital, College of Medicine, Chung-Ang University, Seoul, 06973, South Korea.
Jung-Ha KimDepartment of Family Medicine, Chung-Ang University Hospital, College of Medicine, Chung-Ang University, Seoul, 06973, South Korea. girlpower219@cau.ac.kr.
Chung-Ang University Hospital · KRGachon University · KRSeoul National University · KRYeungnam University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolypharmacy and the use of potentially inappropriate medications are common among nursing home residents and are associated with negative outcomes. Although deprescribing has been proposed as a way to curtail these problems, the best way to implement multidisciplinary comprehensive medication review and deprescribing and its real impact in specific high-risk populations, such as nursing home residents, is still unclear. This multicenter randomized controlled clinical trial aims to assess the effects of a multidisciplinary mediation management program on medication use and health problems.

methodsA total of 1,672 residents aged ≥ 65 years from 22 nursing homes in South Korea who meet the targeted criteria, such as the use of ≥ 10 medications, are eligible to participate. The experimental group will receive a comprehensive medication review, deprescription, and multidisciplinary case conference with the help of platform. Outcomes will be measured at baseline, at the end of the intervention, as well as at 3, 6, 9, and 12 months after the end of the intervention. The primary endpoints will be the rate of adverse drug events, number of potentially inappropriate medications/potentially inappropriate medication users/two or more central nervous system drug/ central nervous system drug users, delirium, emergency department visits, hospitalization, and falls. The secondary endpoint will be the number of medications taken and polypharmacy users. DISCUSSION: Our trial design is unique in that it aims to introduce a structured operationalized clinical program focused on reducing polypharmacy and potentially inappropriate medications in a nursing home setting with large samples.

trial registrationEthical approval was granted by the public institutional review board of the Ministry of Health and Welfare (2022-1092-009). The study is also registered with the Clinical Research Information Service (Identifier: KCT0008157, Development and evaluation of a multidisciplinary medication management program in long-term care facility residents Status: Approved First Submitted Date: 2023/01/18 Registered Date: 2023/02/03 Last Updated Date: 2023/01/18 (nih.go.kr) https://cris.nih.go.kr/ ), which includes all items from the World Health Organization Trial Registration Dataset.

Indexed as

Drug-Related Side Effects and Adverse ReactionsMedication Therapy ManagementCentral Nervous System AgentsHumansMulticenter Studies as TopicNursing HomesRandomized Controlled Trials as TopicSkilled Nursing FacilitiesCentral Nervous System AgentsComprehensive medication reviewDeprescribingLong-term care facility residentsMultidisciplinary medication managementPolypharmacy

Identifiers

PMID38438996
PMCPMC10910765
OpenAlexW4392370372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.