Evidence map›Paper›PMID 38438981›Full record

ArticleBMC geriatrics2024

Age- and sex-specific associations of frailty with mortality and healthcare utilization in community-dwelling adults from ontario, Canada.

Chris P Verschoor, Olga Theou, Jinhui Ma, Phyllis Montgomery, Sharolyn Mossey, Parveen Nangia, Refik Saskin, David W Savage

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC geriatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Chris P VerschoorHealth Sciences North Research Institute, Sudbury, ON, Canada. cverschoor@hsnri.ca.
Olga TheouSchool of Physiotherapy, Dalhousie University, Halifax, NS, Canada.
Jinhui MaDept. of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Phyllis MontgomerySchool of Nursing, Laurentian University, Sudbury, ON, Canada.
Sharolyn MosseySchool of Nursing, Laurentian University, Sudbury, ON, Canada.
Parveen NangiaSchool of Social Sciences, Laurentian University, Sudbury, ON, Canada.
Refik SaskinICES, Toronto, ON, Canada.
David W SavageHealth Sciences North Research Institute, Sudbury, ON, Canada.
Laurentian University · CAHealth Sciences North · CADalhousie University · CAImpact · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUnderstanding how health trajectories are related to the likelihood of adverse outcomes and healthcare utilization is key to planning effective strategies for improving health span and the delivery of care to older adults. Frailty measures are useful tools for risk stratification in community-based and primary care settings, although their effectiveness in adults younger than 60 is not well described.

methodsWe performed a 10-year retrospective analysis of secondary data from the Ontario Health Study, which included 161,149 adults aged ≥ 18. Outcomes including all-cause mortality and hospital admissions were obtained through linkage to ICES administrative databases with a median follow-up of 7.1-years. Frailty was characterized using a 30-item frailty index.

resultsFrailty increased linearly with age and was higher for women at all ages. A 0.1-increase in frailty was significantly associated with mortality (HR = 1.47), the total number of outpatient (IRR = 1.35) and inpatient (IRR = 1.60) admissions over time, and length of stay (IRR = 1.12). However, with exception to length of stay, these estimates differed depending on age and sex. The hazard of death associated with frailty was greater at younger ages, particularly in women. Associations with admissions also decreased with age, similarly between sexes for outpatient visits and more so in men for inpatient.

conclusionsThese findings suggest that frailty is an important health construct for both younger and older adults. Hence targeted interventions to reduce the impact of frailty before the age of 60 would likely have important economic and social implications in both the short- and long-term.

Indexed as

FrailtyAgedFemaleHumansIndependent LivingMaleOntarioPatient Acceptance of Health CareRetrospective StudiesAgingFrailty indexHealthcare utilizationHospital admissionMortality

Identifiers

PMID38438981
PMCPMC10913570
OpenAlexW4392382843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.