Evidence map›Paper›PMID 38438879›Full record

ArticleCancer imaging : the official publication of the International Cancer Imaging Society2024

Clinical outcomes of percutaneous microwave ablation for pulmonary oligometastases from hepatocellular carcinoma: a retrospective, multicenter study.

Gang Wang, Zhigang Wei, Feihang Wang, Xiaoying Han, Haipeng Jia, Danyang Zhao, Chunhai Li, Lingxiao Liu, Xia Yang, Xin Ye

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Cancer imaging : the official publication of the International Cancer Imaging Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Gang Wang *Department of Oncology, Shandong Key Laboratory of Rheumatic Disease and Translational Medicine, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Lung Cancer Institute, 16766 Jingshi Road, 250021, Jinan, Shandong, China.
Zhigang Wei *Department of Oncology, Shandong Key Laboratory of Rheumatic Disease and Translational Medicine, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Lung Cancer Institute, 16766 Jingshi Road, 250021, Jinan, Shandong, China.
Feihang Wang *Department of Interventional Radiology, Zhongshan Hospital, Fudan University, 200032, Shanghai, China.
Xiaoying HanDepartment of Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250014, Jinan, Shandong, China.
Haipeng JiaDepartment of Radiology, Qilu Hospital of Shandong University, 250012, Jinan, China.
Danyang ZhaoDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, 200032, Shanghai, China.
Chunhai LiDepartment of Radiology, Qilu Hospital of Shandong University, 250012, Jinan, China. miami305@126.com.
Lingxiao LiuDepartment of Interventional Radiology, Zhongshan Hospital, Fudan University, 200032, Shanghai, China. liulingxiao2022@163.com.
Xia YangDepartment of Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, 250014, Jinan, Shandong, China. yangxia_jinan@163.com.
Xin YeDepartment of Oncology, Shandong Key Laboratory of Rheumatic Disease and Translational Medicine, The First Affiliated Hospital of Shandong First Medical University & Shandong Provincial Qianfoshan Hospital, Shandong Lung Cancer Institute, 16766 Jingshi Road, 250021, Jinan, Shandong, China. yexintaian2020@163.com.
Fudan University · CNQilu Hospital of Shandong University · CNShandong Provincial Hospital · CNShandong Provincial QianFoShan Hospital · CNShandong First Medical University · CNZhongshan Hospital · CN

Funding

National Natural Science Foundation of China 81502610Natural Science Foundation of Shandong Province ZR201911040313
6 · The paper itself

Abstract

backgroundPulmonary oligometastases are common in hepatocellular carcinoma (HCC), however, the existing therapeutic options have several limitations. This study aimed to assess the safety and efficacy of microwave ablation (MWA) in the treatment of HCC-originating pulmonary oligometastases.

methodsA total of 83 patients, comprising 73 males and 10 females with a median age of 57 years, who had pulmonary oligometastases from HCC, underwent MWA treatment at four different medical institutions. Inclusion criteria for patients involved having primary HCC under control and having less than three oligometastases with a maximum diameter of ≤ 5 cm in the unilateral lung or less than five oligometastases with a maximum diameter of ≤ 3 cm in the bilateral lung. A total of 147 tumors were treated with MWA over 116 sessions. The primary endpoints assessed included technical success, treatment efficacy, and local progression rate, while secondary endpoints encompassed complications, clinical outcomes, overall survival (OS), local progression-free survival (LPFS), and prognostic factors.

resultsThe technical success rate for MWA was 100% (116/116 sessions), and the treatment efficacy rate was 82.3% (121/147 tumors). Six months after MWA, the local progression rate was 23.1% (18/147 tumors). Complications were observed in 10.3% (major) and 47.4% (minor) of the 116 sessions, with no cases of ablation-related deaths. The median follow-up period was 21.6 months (range: 5.7-87.8 months). Median OS was 22.0 months, and the 1-, 2-, and 3-year OS rates were 82.6%, 44.5%, and 25.2%, respectively. Median LPFS was 8.5 months. Multivariate Cox regression analysis identified α-fetoprotein (AFP) levels during initial diagnosis and the number of oligometastases as potential independent prognostic factors for OS (p = 0.017 and 0.045, respectively).

conclusionPercutaneous MWA is a safe and effective treatment modality for pulmonary oligometastases originating from HCC.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsFemaleHumansLungMaleMicrowavesMiddle AgedRetrospective StudiesHepatocellular carcinomaMicrowave ablationMulticenter studyPulmonary oligometastases

Identifiers

PMID38438879
PMCPMC10913397
OpenAlexW4392380385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.