ArticleScientific reports2024
Investigation of periodontal disease development and Porphyromonas gulae FimA genotype distribution in small dogs.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 22 citations in OpenAlex.
- Whole mastic resin ameliorates halitosis and gingivitis in dogs and cats infected with Porphyromonas gulae.Scientific reports · 2025Article
- Review
- Cetylpyridinium chloride and platinum nanoparticles effects in dogs with Porphyromonas gulae-infected periodontal disease.Veterinary research communications · 2025Article
- Multiwave Locked System Laser Treatment Reduces the Bacterial Load in the Gingival Sulcus of Dogs After Plaque Removal.Veterinary sciences · 2025Article
- Possible correlation of specific bacteria detected by using a novel screening method and periodontal disease in dogs.The Journal of veterinary medical science · 2025Article
- A Case of Severe Early Childhood Caries Occurring in a Childhood Cancer Patient.Children (Basel, Switzerland) · 2025Article
- Case Study of a Broken Instrument in a Primary Tooth and Literature Review.Children (Basel, Switzerland) · 2025Article
- A Case of Hypophosphatasia Started Enzyme Replacement Therapy Since Babyhood Stage.Children (Basel, Switzerland) · 2025Article
- Cyclodextran preventsFrontiers in oral health · 2025Article
- Microbial therapeutics for canine periodontal disease: current status and future perspectives.Frontiers in veterinary science · 2025Review
- Usefulness of Generative Artificial Intelligence (AI) Tools in Pediatric Dentistry.Diagnostics (Basel, Switzerland) · 2024Article
- Relationship Between the Presence of Red Complex Species and the Distribution of Other Oral Bacteria, Including Major Periodontal Pathogens in Older Japanese Individuals.International journal of molecular sciences · 2024Article
- Age-correlated changes in the canine oral microbiome.Frontiers in microbiology · 2024Article
- Article
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Authors and funding
16 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In dogs, Porphyromonas gulae is a major periodontal pathogen with 41-kDa proteins polymerizing to form a filamentous structure called fimbriae or pili, termed FimA. FimA is classified into three genotypes: A, B, and C, and there are combinations of types A, B, C, A/B, A/C, B/C, and A/B/C. Periodontal disease is the most common oral disease in small dogs, but the periodontal disease status and P. gulae colonization at each dog age and breed remain unclear. In this study, we stratified 665 small dogs and analyzed the periodontal status and distribution of P. gulae with each FimA genotype. Dogs with periodontal disease and FimA genotype tended to increase with age. The dogs with at least one FimA genotype had significantly more severe periodontal disease compared with P. gulae-negative dogs (P < 0.01). Additionally, periodontal status was significantly associated with specific FimA genotype distribution in Toy Poodles and Chihuahuas (P < 0.05), whereas there was no such association in Dachshunds. These results suggest that the onset of periodontal disease and P. gulae colonization are related and progress with age. The relationship between periodontal disease and FimA genotype may differ depending on the dog breeds.
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