ArticleScientific reports2024
Impacts of optimal control strategies on the HBV and COVID-19 co-epidemic spreading dynamics.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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15 citing papers in PubMed.
- Analysis, control, and forecasting the dynamics of SIRD models with saturated treatment and nonlinear incidence.Scientific reports · 2026Article
- A data-driven approach to hepatitis C forecasting using machine learning and epidemiological models.PloS one · 2026Article
- HIV/AIDS compartmental model analysis with drug resistance treatment, vertical transmission, and optimal control theory.Scientific reports · 2025Article
- Mathematical modelling and time series clustering of Mpox outbreak: A comparative study of the top 10 affected countries and implications for future outbreak management.Global epidemiology · 2025Article
- Optimal intervention design for tonsillitis transmission via compartmental modeling with stability analysis and control strategies.Scientific reports · 2025Article
- Discussing the epidemiology of COVID-19 model with the effective numerical scheme.Scientific reports · 2025Article
- Resurgence in focus: Covid-19 dynamics and optimal control frameworks.Global epidemiology · 2025Article
- A mathematical framework of HIV and TB co-infection dynamics.Scientific reports · 2025Article
- Stability and control analysis of COVID-19 spread in India using SEIR model.Scientific reports · 2025Article
- Analyses of an age structure HIV/AIDS compartmental model with optimal control theory.Scientific reports · 2025Article
- HIV/AIDS and HBV co-infection with optimal control strategies and cost-effectiveness analyses using integer order model.Scientific reports · 2025Article
- A new epidemic model of sexually transmittable diseases: a fractional numerical approach.Scientific reports · 2025Article
- Dynamical analysis of methicillin-resistant Staphylococcus aureus infection in North Cyprus with optimal control: prevalence and awareness.Scientific reports · 2024Article
- Article
- A dynamical optimal control theory and cost-effectiveness analyses of the HBV and HIV/AIDS co-infection model.Frontiers in public health · 2024Article
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Abstract
Different cross-sectional and clinical research studies investigated that chronic HBV infected individuals' co-epidemic with COVID-19 infection will have more complicated liver infection than HBV infected individuals in the absence of COVID-19 infection. The main objective of this study is to investigate the optimal impacts of four time dependent control strategies on the HBV and COVID-19 co-epidemic transmission using compartmental modeling approach. The qualitative analyses of the model investigated the model solutions non-negativity and boundedness, calculated all the models effective reproduction numbers by applying the next generation operator approach, computed all the models disease-free equilibrium point (s) and endemic equilibrium point (s) and proved their local stability, shown the phenomenon of backward bifurcation by applying the Center Manifold criteria. By applied the Pontryagin's Maximum principle, the study re-formulated and analyzed the co-epidemic model optimal control problem by incorporating four time dependent controlling variables. The study also carried out numerical simulations to verify the model qualitative results and to investigate the optimal impacts of the proposed optimal control strategies. The main finding of the study reveals that implementation of protections, COVID-19 vaccine, and treatment strategies simultaneously is the most effective optimal control strategy to tackle the HBV and COVID-19 co-epidemic spreading in the community.
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