Evidence map›Paper›PMID 38437913›Full record

ArticleNeuropharmacology2024

Quantitative T

Alita Jesal D Almeida, Brad A Hobson, Naomi Saito, Donald A Bruun, Valerie A Porter, Danielle J Harvey, Joel R Garbow, Abhijit J Chaudhari, Pamela J Lein

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neuropharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Alita Jesal D AlmeidaDepartment of Biomedical Engineering, University of California-Davis College of Engineering, Davis, CA, 95616, USA; Department of Radiology, University of California-Davis School of Medicine, Sacramento, CA, 95817, USA. Electronic address: ajdalmeida@ucdavis.edu.
Brad A HobsonCenter for Molecular and Genomic Imaging, Department of Biomedical Engineering, University of California-Davis College of Engineering, Davis, CA, 95616, USA. Electronic address: bahobson@ucdavis.edu.
Naomi SaitoDepartment of Public Health Sciences, University of California-Davis School of Medicine, Davis, CA, 95616, USA.
Donald A BruunDepartment of Molecular Biosciences, University of California-Davis School of Veterinary Medicine, Davis, CA, 95616, USA. Electronic address: dabruun@ucdavis.edu.
Valerie A PorterDepartment of Biomedical Engineering, University of California-Davis College of Engineering, Davis, CA, 95616, USA; Department of Radiology, University of California-Davis School of Medicine, Sacramento, CA, 95817, USA. Electronic address: vporter@ucdavis.edu.
Danielle J HarveyDepartment of Public Health Sciences, University of California-Davis School of Medicine, Davis, CA, 95616, USA. Electronic address: djharvey@ucdavis.edu.
Joel R GarbowDepartment of Radiology, Washington University School of Medicine, St Louis, MO, 63110, USA. Electronic address: garbow@wustl.edu.
Abhijit J ChaudhariDepartment of Radiology, University of California-Davis School of Medicine, Sacramento, CA, 95817, USA; Center for Molecular and Genomic Imaging, Department of Biomedical Engineering, University of California-Davis College of Engineering, Davis, CA, 95616, USA. Electronic address: ajchaudhari@ucdavis.edu.
Pamela J LeinDepartment of Molecular Biosciences, University of California-Davis School of Veterinary Medicine, Davis, CA, 95616, USA. Electronic address: pjlein@ucdavis.edu.
University of California, Davis · USWashington University in St. Louis · US

Funding

UC Davis Clinical and Translational Science CenterUL1TR001860 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KENYON, NICHOLAS J., LYLES, COURTNEY REES · 2016 to 2025
$47.3M
Training and Education CoreU54NS079202 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEIN, PAMELA J · 2012 to 2021
$35.7M
UC Davis CounterACT Center of Excellence: Developing Therapeutic Strategies for Mitigating the Chronic Neurological Consequences of Acute Organophosphate IntoxicationU54NS127758 · NINDS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Pamela J Lein · 2022 to 2026
$17.2M
UC Davis CTSC TL1 Administrative Supplement to Recognize Excellence in Diversity, Equity, Inclusion, and Accessibility MentorshipTL1TR001861 · NCATS · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MEDICI, VALENTINA · 2016 to 2025
$4.7M
Imaging biomarkers of early synaptic changes in a preclinical model of Alzheimer’s diseaseR21AG064599 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI CHAUDHARI, ABHIJIT J, LEIN, PAMELA J · 2019 to 2020
$432k
NCATS NIH HHS TL1 TR001861NCATS NIH HHS UL1 TR001860NIA NIH HHS R21 AG064599NINDS NIH HHS U54 NS079202NINDS NIH HHS U54 NS127758
6 · The paper itself

Abstract

Acute intoxication with organophosphate (OP) cholinesterase inhibitors poses a significant public health risk. While currently approved medical countermeasures can improve survival rates, they often fail to prevent chronic neurological damage. Therefore, there is need to develop effective therapies and quantitative metrics for assessing OP-induced brain injury and its rescue by these therapies. In this study we used a rat model of acute intoxication with the OP, diisopropylfluorophosphate (DFP), to test the hypothesis that T

Indexed as

Brain InjuriesOrganophosphate PoisoningAnimalsBrainCholinesterase InhibitorsIsoflurophateMaleMidazolamOrganophosphatesRatsRats, Sprague-DawleyCholinesterase InhibitorsIsoflurophateMidazolamOrganophosphatesAllopregnanoloneDiisopropylfluorophosphateMagnetic resonance imagingMidazolamNeurosteroidT(2) mapping

Identifiers

PMID38437913
PMCPMC11227117
OpenAlexW4392349909

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.