Evidence map›Paper›PMID 38437620›Full record

ArticleJournal of veterinary internal medicine

Environmental radon, fracking wells, and lymphoma in dogs.

Ashleigh N Tindle, Samantha L Braman, Brenna M Swafford, Lauren A Trepanier

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Environmental radon, fracking wells, and lymphoma in dogs.Journal of veterinary internal medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ashleigh N TindleDepartment of Medical Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Samantha L BramanDepartment of Medical Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Brenna M SwaffordMorris Animal Foundation, Denver, Colorado, USA.
Lauren A TrepanierDepartment of Medical Sciences, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0001-8585-7350
University of Wisconsin–Madison · USMorris Animal Foundation · US

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
NRSA Training CoreTL1TR002375 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI Vivek Prabhakaran · 2017 to 2026
$8.4M
Morris Animal FoundationNCATS NIH HHS TL1 TR002375NCATS NIH HHS TL1TR002375NCATS NIH HHS U54TR002373NCATS NIH HHS UL1 TR002373
6 · The paper itself

Abstract

backgroundMulticentric lymphoma (ML) in dogs resembles non-Hodgkin lymphoma (NHL) in humans. Human NHL is associated with multiple environmental exposures, including to radon and volatile organic compounds (VOCs). HYPOTHESIS/

objectivesThe objective of this study was to determine whether ML in dogs was associated with environmental radon or proximity to horizontal oil and drilling (fracking), a source of VOC pollution.

methodsWe identified dogs from the Golden Retriever Lifetime Study that developed ML (n = 52) along with matched controls (n = 104). Dog home addresses were categorized by Environmental Protection Agency radon zone and average residential radon by county, as well as by distance from fracking and associated wastewater wells.

resultsWe found no significant differences in county level radon measurements. Individual household radon measurements were not available. There was no difference in residential proximity to active fracking wells between dogs with ML and unaffected dogs. While dogs with ML lived closer to wastewater wells (123 vs 206 km; P = .01), there was no difference in the percentage of cases vs controls that lived in close proximity (20 km) to a fracking well (11.5% for cases, 6.7% for controls; OR 1.81, 95% CI 0.55 to 5.22; P = .36), or a wastewater well (6.7% for cases, 4.4% for controls; P > .99). CONCLUSIONS AND CLINICAL IMPORTANCE: These data suggest that more proximate sources of chemical exposures need to be assessed in dogs with ML, including measurements of individual household radon and household VOC concentrations.

Indexed as

Dog DiseasesEnvironmental ExposureRadonAnimalsCase-Control StudiesDogsFemaleHydraulic FrackingLymphomaMaleVolatile Organic CompoundsRadonVolatile Organic Compoundsclass II injection wellsfrackinghorizontal drillingmulticentric lymphomanon‐Hodgkin lymphomavolatile organic compoundswastewater

Identifiers

PMID38437620
PMCPMC11099769
OpenAlexW4392383742

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.