ArticleProceedings of the National Academy of Sciences of the United States of America2024
Ingested soil bacteria breach gut epithelia and prime systemic immunity in an insect.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Article
- Fidelity in co-diversified symbiosis.Nature communications · 2026Article
- Gut microbiota-derived butyrate primes systemic immunity in honey bees by mediating lipid metabolic reprogramming.Nature communications · 2026Article
- Late is not great: fitness implications of delayed symbiont acquisition.Frontiers in microbiology · 2026Article
- Immune priming reshapes the microbiota and modulates pathogen dynamics in the Manila clam (Frontiers in microbiology · 2026Article
- Cultivation substrates alter plant metabolic profiles with concomitant impacts on herbivore performance.Frontiers in microbiology · 2026Article
- Multi-Habitat Landscape Promotes Microbial Diversity: Insights from the Traditional Agricultural Heritage and the Global Trend.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Gut bacteria induce heterologous immune priming in Rhodnius prolixus encompassing both humoral and cellular immune responses.PLoS pathogens · 2025Article
- Wild gut microbiome suppresses the potentially opportunistic pathogen Aeromonas in medaka under domesticated rearing conditions.Animal microbiome · 2025Article
- Immune priming in the insect gut: a dynamic response revealed by ultrastructural and transcriptomic changes.BMC biology · 2025Article
- Different Long-Term Nutritional Regimens ofInsects · 2025Article
- Strict gut symbiont specificity in Coreoidea insects governed by interspecies competition within Caballeronia strains.The ISME journal · 2025Article
- Article
- Hundreds of antimicrobial peptides create a selective barrier for insect gut symbionts.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Bugs promote immune priming via gut-breaching bacteria.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- How many do we need? Meeting the challenges of studying the microbiome of a cryptic insect in an orchard.Frontiers in microbiology · 2024Article
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 2 countries.
Funding
Abstract
Insects lack acquired immunity and were thought to have no immune memory, but recent studies reported a phenomenon called immune priming, wherein sublethal dose of pathogens or nonpathogenic microbes stimulates immunity and prevents subsequential pathogen infection. Although the evidence for insect immune priming is accumulating, the underlying mechanisms are still unclear. The bean bug
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.