Evidence map›Paper›PMID 38437472›Full record

ReviewPolish journal of microbiology2024

Sugar Utilization-Associated Food-Grade Selection Markers in Lactic Acid Bacteria and Yeast.

Zhiwen Liang, Ke Zheng, Guifeng Xie, Xiongsheng Luo, Huangjin Li

Open access · goldAbstract readReview
In one paragraph

Review in Polish journal of microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Zhiwen Liang1School of Life and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Ke Zheng1School of Life and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Guifeng Xie2Guangzhou MEIZHONG Biotechnology Co., Ltd, Guangzhou, China.
Xiongsheng Luo2Guangzhou MEIZHONG Biotechnology Co., Ltd, Guangzhou, China.
Huangjin Li1School of Life and Biopharmaceutics, Guangdong Pharmaceutical University, Guangzhou, China.
Guangdong Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This comprehensive review explores the development of food-grade selection markers in lactic acid bacteria and yeast; some of their strains are precisely defined as safe microorganisms and are crucial in the food industry. Lactic acid bacteria, known for their ability to ferment carbohydrates into lactic acid, provide essential nutrients and contribute to immune responses. With its strong fermentation capabilities and rich nutritional profile, yeast finds use in various food products. Genetic engineering in these microorganisms has grown rapidly, enabling the expression of enzymes and secondary products for food production. However, the focus is on ensuring safety, necessitating food-grade selection markers. Traditional antibiotic and heavy metal resistance selection markers pose environmental and health risks, prompting the search for safer alternatives. Complementary selection markers, such as sugar utilization markers, offer a promising solution. These markers use carbohydrates as carbon sources for growth and are associated with the natural metabolism of lactic acid bacteria and yeast. This review discusses the use of specific sugars, such as lactose, melibiose, sucrose, D-xylose, glucosamine, and N-acetylglucosamine, as selection markers, highlighting their advantages and limitations. In summary, this review underscores the importance of food-grade selection markers in genetic engineering and offers insights into their applications, benefits, and challenges, providing valuable information for researchers in the field of food microbiology and biotechnology.

Indexed as

LactobacillalesSaccharomyces cerevisiaeAnti-Bacterial AgentsBiotechnologyCarbohydratesAnti-Bacterial AgentsCarbohydratesfood-gradegenetic engineeringGRASlactic acid acid bacteriaselection markeryeast

Identifiers

PMID38437472
PMCPMC10911659
OpenAlexW4392380463

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.