Evidence map›Paper›PMID 38437468›Full record

ArticlePolish journal of microbiology2024

A Mendelian Randomization Study: Roles of Gut Microbiota in Sepsis - Who is the Angle?

Yeping Bian, Jian Xu, Xiaojing Deng, Suming Zhou

Open access · goldAbstract read
In one paragraph

Article in Polish journal of microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yeping Bian1Department of Intensive Care Unit, Geriatric Hospital of Nanjing Medical University, Nanjing, China.
Jian Xu1Department of Intensive Care Unit, Geriatric Hospital of Nanjing Medical University, Nanjing, China.
Xiaojing Deng1Department of Intensive Care Unit, Geriatric Hospital of Nanjing Medical University, Nanjing, China.
Suming Zhou2Department of Geriatrics Intensive Care Unit, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbiota (GM) is a crucial underlying player during sepsis pathogenesis. However, the causal relationship is unclear and remains to be determined. A two-sample Mendelian randomization study was implemented. The statistical data about sepsis together with GM summarized from genome-wide association studies were evaluated. Instrumental variables were defined as single-nucleotide polymorphisms with prominent correlations with exposure. The inverse-variance-weighted test was employed as a major approach of Mendelian randomization analysis to estimate of causal relationships. The inverse-variance-weighted analysis results demonstrated that at different taxa levels, Actinobacteria and

Indexed as

ActinobacteriaGastrointestinal MicrobiomeSepsisGenome-Wide Association StudyHumansMendelian Randomization Analysiscausal relationshipgut microbiotaMendelian randomizationsepsis

Identifiers

PMID38437468
PMCPMC10911657
OpenAlexW4392369002

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.