Evidence map›Paper›PMID 38436693›Full record

ReviewAnalytical and bioanalytical chemistry2024

Application of gold nanoclusters in fluorescence sensing and biological detection.

Kexin Tan, Huizhen Ma, Xiaoyu Mu, Zhidong Wang, Qi Wang, Hao Wang, Xiao-Dong Zhang

Abstract readReview
PubMed Publisher
In one paragraph

Review in Analytical and bioanalytical chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kexin Tan *Tianjin Key Laboratory of Brain Science and Neural Engineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, 300072, China.
Huizhen Ma *Tianjin Key Laboratory of Brain Science and Neural Engineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, 300072, China.
Xiaoyu MuTianjin Key Laboratory of Brain Science and Neural Engineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, 300072, China.
Zhidong WangDepartment of Radiobiology, Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, China.
Qi WangDepartment of Radiobiology, Beijing Key Laboratory for Radiobiology, Beijing Institute of Radiation Medicine, Beijing, China. wqi619@126.com.
Hao WangTianjin Key Laboratory of Brain Science and Neural Engineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, 300072, China. hao_wang@tju.edu.cn.
Xiao-Dong ZhangTianjin Key Laboratory of Brain Science and Neural Engineering, Academy of Medical Engineering and Translational Medicine, Tianjin University, Tianjin, 300072, China. xiaodongzhang@tju.edu.cn.

Funding

National Natural Science Foundation of Tianjin 19JCZDJC34000National Natural Science Foundation of Tianjin 20JCYBJC00940National Natural Science Foundation of Tianjin 21JCYBJC00490National Natural Science Foundation of Tianjin 21JCYBJC00550National Natural Science Foundation of Tianjin 21JCZDJC00620Outstanding Youth Funds of Tianjin 2021FJ-0009the Innovation Foundation of Tianjin University, and CAS Interdisciplinary Innovation Team JCTD-2020-08the National Key Research and Development Program of China 2021YFF1200700the National Natural Science Foundation of China 11804248the National Natural Science Foundation of China 81971744the National Natural Science Foundation of China 82001952the National Natural Science Foundation of China 82302361the National Natural Science Foundation of China 82302381the National Natural Science Foundation of China 91859101the National Natural Science Foundation of China U1932107
6 · The paper itself

Abstract

Gold nanoclusters (Au NCs) exhibit broad fluorescent spectra from visible to near-infrared regions and good enzyme-mimicking catalytic activities. Combined with excellent stability and exceptional biocompatibility, the Au NCs have been widely exploited in biomedicine such as biocatalysis and bioimaging. Especially, the long fluorescence lifetime and large Stokes shift attribute Au NCs to good probes for fluorescence sensing and biological detection. In this review, we systematically summarized the molecular structure and fluorescence properties of Au NCs and highlighted the advances in fluorescence sensing and biological detection. The Au NCs display high sensitivity and specificity in detecting iodine ions, metal ions, and reactive oxygen species, as well as certain diseases based on the fluorescence activities of Au NCs. We also proposed several points to improve the practicability and accelerate the clinical translation of the Au NCs.

Indexed as

GoldMetal NanoparticlesAnimalsBiosensing TechniquesFluorescenceFluorescent DyesHumansReactive Oxygen SpeciesSpectrometry, FluorescenceFluorescent DyesGoldReactive Oxygen SpeciesBiological detectionFluorescence sensingGold nanoclustersPhotoluminescence

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.