Evidence map›Paper›PMID 38436260›Full record

ArticleThe Journal of international medical research2024

Biomarker cystatin B expression correlates with pathogenesis in cervical cancer.

Danjuan Ye, Xiaoling Duan, Bin Guan, Jia Yuan, Yan Zhu, Jimin Shi, Qi Lu, Guoxiong Xu

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Danjuan YeDepartment of Obstetrics and Gynaecology, Jinshan Hospital, Fudan University, Shanghai, P. R. China.
Xiaoling DuanDepartment of Obstetrics and Gynaecology, Jinshan Hospital, Fudan University, Shanghai, P. R. China.
Bin GuanResearch Center for Clinical Medicine, Jinshan Hospital, Fudan University, Shanghai, P. R. China.
Jia YuanResearch Center for Clinical Medicine, Jinshan Hospital, Fudan University, Shanghai, P. R. China.
Yan ZhuResearch Center for Clinical Medicine, Jinshan Hospital, Fudan University, Shanghai, P. R. China.
Jimin ShiResearch Center for Clinical Medicine, Jinshan Hospital, Fudan University, Shanghai, P. R. China.
Qi LuDepartment of Obstetrics and Gynaecology, Jinshan Hospital, Fudan University, Shanghai, P. R. China.
Guoxiong XuResearch Center for Clinical Medicine, Jinshan Hospital, Fudan University, Shanghai, P. R. China.ORCID 0000-0002-9074-8754
Jinshan Hospital of Fudan University · CNShanghai Medical College of Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCervical cancer (CC) is one of the most common gynecologic malignancies worldwide. Although rapid improvements have been made regarding its prevention and treatment, little is known about disease pathogenesis and the clinical relevance of reliable biomarkers. The present study evaluated the expression of cystatin B (CSTB) as a potential biomarker of CC.

methodsTissue microarray analysis and immunohistochemical staining were performed to detect CSTB expression, while

resultsWe observed high

conclusionOur data demonstrate that CSTB has the potential to be used as a tissue biomarker with clinical value in patients with CC, which may aid the development of intervention strategies.

Indexed as

Cystatin BUterine Cervical NeoplasmsBiomarkersBlotting, WesternFemaleHumansRNA, MessengerBiomarkersCystatin BRNA, Messengercervical cancerCystatin Blesionpathological progresstissue microarraytumor

Identifiers

PMID38436260
PMCPMC10913530
OpenAlexW4392369813

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.