Evidence map›Paper›PMID 38436067›Full record

ArticleGut microbes

Gut microbiota-palmitoleic acid-interleukin-5 axis orchestrates benzene-induced hematopoietic toxicity.

Lei Zhang, Ziyan Liu, Wei Zhang, Jingyu Wang, Huiwen Kang, Jiaru Jing, Lin Han, Ai Gao

Open access · goldAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Lei ZhangDepartment of Occupational Health and Environmental Health, School of Public Health, Capital Medical University, Beijing, China.
Ziyan LiuDepartment of Occupational Health and Environmental Health, School of Public Health, Capital Medical University, Beijing, China.
Wei ZhangDepartment of Occupational Health and Environmental Health, School of Public Health, Capital Medical University, Beijing, China.
Jingyu WangDepartment of Occupational Health and Environmental Health, School of Public Health, Capital Medical University, Beijing, China.
Huiwen KangDepartment of Occupational Health and Environmental Health, School of Public Health, Capital Medical University, Beijing, China.
Jiaru JingDepartment of Occupational Health and Environmental Health, School of Public Health, Capital Medical University, Beijing, China.
Lin HanDepartment of Occupational Health and Environmental Health, School of Public Health, Capital Medical University, Beijing, China.
Ai GaoDepartment of Occupational Health and Environmental Health, School of Public Health, Capital Medical University, Beijing, China.ORCID 0000-0002-0764-4656
Capital Medical University · CNBinzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the annual increase in its production and consumption in occupational environments, the adverse blood outcomes caused by benzene are of concern. However, the mechanism of benzene-induced hematopoietic damage remains elusive. Here, we report that benzene exposure causes hematopoietic damage in a dose-dependent manner and is associated with disturbances in gut microbiota-long chain fatty acids (LCFAs)-inflammation axis. C57BL/6J mice exposed to benzene for 45 days were found to have a significant reduction in whole blood cells and the suppression of hematopoiesis, an increase in

Indexed as

Fatty Acids, MonounsaturatedGastrointestinal MicrobiomeInterleukin-5AnimalsBenzeneFatty AcidsInflammationMiceMice, Inbred C57BLBenzeneFatty AcidsFatty Acids, MonounsaturatedInterleukin-5palmitoleic acidBenzenegut microbiotahematotoxicitylong-chain fatty acidsprobiotics

Identifiers

PMID38436067
PMCPMC10913712
OpenAlexW4392374438

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.