Evidence map›Paper›PMID 38436040›Full record

ArticleDrug design, development and therapy2024

Synthesis of a New Series of Anthraquinone-Linked Cyclopentanone Derivatives: Investigating the Antioxidant, Antibacterial, Cytotoxic and Tyrosinase Inhibitory Activities of the Mushroom Tyrosinase Enzyme Using Molecular Docking.

Janani Mullaivendhan, Idhayadhulla Akbar, Anis Ahamed, Mansour K Gatasheh, Ashraf Atef Hatamleh, Gurusamy Raman, Aseer Manilal, Sabu Kuzhunellil Raghavanpillai

Abstract read
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In one paragraph

Article in Drug design, development and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Bioactive Furan Derivatives fromCurrent drug discovery technologies · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Janani MullaivendhanResearch Department of Chemistry, Nehru Memorial College (Affiliated to Bharathidasan University), Puthanampatti, Tamil Nadu, 621007, India.
Idhayadhulla AkbarResearch Department of Chemistry, Nehru Memorial College (Affiliated to Bharathidasan University), Puthanampatti, Tamil Nadu, 621007, India.ORCID 0000-0003-0309-6274
Anis AhamedDepartment of Botany and Microbiology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
Mansour K GatashehDepartment of Biochemistry, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.
Ashraf Atef HatamlehDepartment of Botany and Microbiology, College of Science, King Saud University, Riyadh, 11451, Saudi Arabia.ORCID 0000-0002-9623-3110
Gurusamy RamanDepartment of Life Science, Yeungnam University, Gyeongsan, Gyeongbuk-do, 38541, South Korea.
Aseer ManilalDepartment of Laboratory Sciences, College of Medicine and Health Sciences, Arba Minch University, Arba Minch, Ethiopia.ORCID 0000-0002-1146-8093
Sabu Kuzhunellil RaghavanpillaiBiogeochemistry Division, VM Clays and Minerals, Thiruvananthapuram, Kerala, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: New bioactive anthraquinone derivatives are investigated for antibacterial, tyrosinase inhibitory, antioxidant cytotoxic activity, and molecular docking. Methods: The compounds were produced using the grindstone method, yielding 69 to 89%. These compounds were analyzed using IR, Results: Compound Conclusion: All synthesized compounds displayed remarkable antibacterial, tyrosinase inhibitory, antioxidant, and cytotoxic activities, with compound

Indexed as

AgaricalesAntineoplastic AgentsCyclopentanesAnthraquinonesAnti-Bacterial AgentsAntioxidantsKineticsMolecular Docking SimulationMonophenol MonooxygenaseAnthraquinonesAnti-Bacterial AgentsAntineoplastic AgentsAntioxidantsCyclopentanescyclopentanoneMonophenol Monooxygenaseanthraquinoneantibacterial activityantioxidant activitybinding affinitycytotoxic activitykojic acidmolecular dockingtyrosinase enzyme

Identifiers

PMID38436040
PMCPMC10908290

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.