Evidence map›Paper›PMID 38436032›Full record

ArticlePeerJ2024

Prognostic factors and outcomes of invasive pulmonary aspergillosis, a retrospective hospital-based study.

Wei-Che Chen, I-Chieh Chen, Jun-Peng Chen, Tsai-Ling Liao, Yi-Ming Chen

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.3field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Wei-Che ChenDivision of Nephrology, Department of Internal Medicine, Taichung Veterans General Hospital, Taiwan.
I-Chieh ChenDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.ORCID 0000-0002-8345-5304
Jun-Peng ChenDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Tsai-Ling LiaoDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Yi-Ming ChenDepartment of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.ORCID 0000-0001-7593-3065
Taichung Veterans General Hospital · TWNational Chung Hsing University · TWNational Yang Ming Chiao Tung University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Invasive pulmonary aspergillosis (IPA) affects immunocompromised hosts and is associated with higher risks of respiratory failure and mortality. However, the clinical outcomes of different IPA types have not been identified. Methods: Between September 2002 and May 2021, we retrospectively enrolled patients with IPA in Taichung Veterans General Hospital, Taiwan. Cases were classified as possible IPA, probable IPA, proven IPA, and putative IPA according to EORTC/MSGERC criteria and the AspICU algorithm. Risk factors of respiratory failure, kidney failure, and mortality were analyzed by logistic regression. A total of 3-year survival was assessed by the Kaplan-Meier method with log-rank test for Results: We included 125 IPA patients (50: possible IPA, 47: probable IPA, 11: proven IPA, and 17: putative IPA). Comorbidities of liver cirrhosis and solid organ malignancy were risk factors for respiratory failure; diabetes mellitus and post-liver or kidney transplantation were related to kidney failure. Higher galactomannan (GM) test optical density index (ODI) in either serum or bronchoalveolar lavage fluid was associated with dismal outcomes. Probable IPA and putative IPA had lower 3-year respiratory failure-free survival compared to possible IPA. Probable IPA and putative IPA exhibited lower 3-year renal failure-free survival in comparison to possible IPA and proven IPA. Putative IPA had the lowest 3-year overall survival rates among the four IPA groups. Conclusion: Patients with putative IPA had higher mortality rates than the possible, probable, or proven IPA groups. Therefore, a prompt diagnosis and timely treatment are warranted for patients with putative IPA.

Indexed as

Invasive Pulmonary AspergillosisRenal InsufficiencyRespiratory InsufficiencyHospitals, GeneralHumansPrognosisRetrospective StudiesInvasive pulmonary aspergillosisMortalityRenal failureRespiratory failureRisk factors

Identifiers

PMID38436032
PMCPMC10908254
OpenAlexW4392234459

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.