Evidence map›Paper›PMID 38435899›Full record

ReviewCureus2024

Botulinum Toxin for the Management of Parkinson's Disease: A Systematic Review.

Ethan Slouha, Fadi Ibrahim, Sarah Esposito, Odelin Mursuli, Atbeen Rezazadah, Lucy A Clunes, Theofanis F Kollias

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 2 pooled it
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 syntheses or guidelines pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Ethan SlouhaPharmacology, St. George's University School of Medicine, St. George's, GRD.
Fadi IbrahimPharmacology, St. George's University School of Medicine, St. George's, GRD.
Sarah EspositoPharmacology, St. George's University School of Medicine, St. George's, GRD.
Odelin MursuliPharmacology, St. George's University School of Medicine, St. George's, GRD.
Atbeen RezazadahPharmacology, St. George's University School of Medicine, St. George's, GRD.
Lucy A ClunesPharmacology, St George's University School of Medicine, St George's, GRD.
Theofanis F KolliasMicrobiology, Immunology, and Pharmacology, St. George's University School of Medicine, St. George's, GRD.
St. George's University · GDSt. George's School · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is a terminal, debilitating neurodegenerative disorder typically affecting individuals over 60. It is associated with various conditions that drastically affect the patient's quality of life (QoL). Although there is no cure for PD, its symptoms can be significantly improved and even resolved through different treatments. Mainstay treatments for PD include levodopa combined with carbidopa, dopamine agonists, and even deep brain stimulation (DBS) of the subthalamic nucleus. New treatment methods have emerged, such as botulinum toxin (BoNT), which further improve symptoms and, thus, the QoL of patients with PD. Botulinum toxin is a potent neurotoxin produced by

Indexed as

botulinum toxindystoniaparkinson's diseasesialorrheatremor

Identifiers

PMID38435899
PMCPMC10906698
OpenAlexW4391383912

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.