Evidence map›Paper›PMID 38435807›Full record

ReviewBiodesign research2024

Advances in the Application of Single-Cell Transcriptomics in Plant Systems and Synthetic Biology.

Md Torikul Islam, Yang Liu, Md Mahmudul Hassan, Paul E Abraham, Jean Merlet, Alice Townsend, Daniel Jacobson, C Robin Buell, Gerald A Tuskan, Xiaohan Yang

Open access · diamondAbstract readReview
In one paragraph

Review in Biodesign research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. Article
  3. ThePlants (Basel, Switzerland) · 2026
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Identification of Phloem Cell Transcriptome via Single-Cell RNA-Sequencing.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  9. Single-Cell/Nucleus RNA-Sequencing for Phytohormone Signaling in Plants.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  10. Review
  11. Review
  12. Article
  13. Opportunities and challenges in the application of single-cell transcriptomics in plant tissue research.Physiology and molecular biology of plants : an international journal of functional plant biology · 2025
    Review
  14. Review
  15. Review
  16. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Md Torikul IslamBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA.
Yang LiuBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA.
Md Mahmudul HassanDepartment of Genetics and Plant Breeding, Patuakhali Science and Technology University, Dumki, Patuakhali 8602, Bangladesh.
Paul E AbrahamBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA.
Jean MerletThe Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA.
Alice TownsendThe Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA.
Daniel JacobsonBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA.
C Robin BuellCenter for Applied Genetic Technologies, University of Georgia, Athens, GA 30602, USA.
Gerald A TuskanBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA.
Xiaohan YangBiosciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831, USA.
Oak Ridge National Laboratory · USUniversity of Tennessee at Knoxville · USPatuakhali Science and Technology University · BDUniversity of Georgia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plants are complex systems hierarchically organized and composed of various cell types. To understand the molecular underpinnings of complex plant systems, single-cell RNA sequencing (scRNA-seq) has emerged as a powerful tool for revealing high resolution of gene expression patterns at the cellular level and investigating the cell-type heterogeneity. Furthermore, scRNA-seq analysis of plant biosystems has great potential for generating new knowledge to inform plant biosystems design and synthetic biology, which aims to modify plants genetically/epigenetically through genome editing, engineering, or re-writing based on rational design for increasing crop yield and quality, promoting the bioeconomy and enhancing environmental sustainability. In particular, data from scRNA-seq studies can be utilized to facilitate the development of high-precision Build-Design-Test-Learn capabilities for maximizing the targeted performance of engineered plant biosystems while minimizing unintended side effects. To date, scRNA-seq has been demonstrated in a limited number of plant species, including model plants (e.g.,

Identifiers

PMID38435807
PMCPMC10905259
OpenAlexW4391392358

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.