Evidence map›Paper›PMID 38435668›Full record

ArticleFrontiers in chemistry2024

Choline chloride/urea as a green and efficient deep eutectic solvent in three-component and four-component synthesis of novel pyrazole and pyrano[2,3-c] pyrazole derivatives with antibacterial and antifungal activity.

Israa Habeeb Naser, Hassan Thoulfikar A Alamir, Ali Hisham Al-Shukarji, Batool Ali Ahmed, Talal Aziz Qassem, Maher Kamal, Tahani M Almeleebia, Enas R Alwaily, Eftikhaar Hasan Kadhum, Ahmed Alawadi and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 9 institutions in 2 countries.

Israa Habeeb NaserMedical Laboratories Techniques Department, Al-Mustaqbal University, Hillah, Iraq.
Hassan Thoulfikar A AlamirFaculty of Pharmacy, Department of Pharmaceutics, University of Al-Ameed, Karbala, Iraq.
Ali Hisham Al-ShukarjiDepartment of Medical Laboratories Technology, Al-Manara College for Medical Sciences, Maysan, Iraq.
Batool Ali AhmedDepartment of Medical Engineering, Al-Nisour University College, Baghdad, Iraq.
Talal Aziz QassemDepartment of Medical Laboratory Technics, Al-Noor University College, Nineveh, Iraq.
Maher KamalDepartment of Dentistry, Al-Hadi University College, Baghdad, Iraq.
Tahani M AlmeleebiaDepartment of Clinical Pharmacy, College of Pharmacy, King Khalid University, Abha, Saudi Arabia.
Enas R AlwailyMicrobiology Research Group, College of Pharmacy, Al-Ayen University, Thi-Qar, Iraq.
Eftikhaar Hasan KadhumNational University of Science and Technology, Dhi Qar, Iraq.
Ahmed AlawadiCollege of Technical Engineering, The Islamic University, Najaf, Iraq.
Ali AlsalamyCollege of Technical Engineering, Imam Ja'afar Al-Sadiq University, Al-Muthanna, Iraq.
Al-Ayen Iraqi University · IQAl-Hadi University CollegeAl-Nisour University College · IQAl Noor University CollegeImam Ja’afar Al-Sadiq UniversityIraqi University · IQKing Khalid University · SAThi Qar University · IQUniversity of Kerbala · IQ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, choline chloride/urea was used as a green deep eutectic solvent in the three-component reaction of hydrazine/phenylhydrazine, malononitrile, and aromatic aldehydes for synthesizing pyrazole derivatives, and in the four-component reaction of methyl/ethyl acetoacetate, hydrazine/phenylhydrazine, malononitrile, and aromatic aldehydes for synthesizing pyrano[2,3-c]pyrazole derivatives. Elemental analysis,

Indexed as

antimicrobial agentbiological evaluationcholine chloride/ureadeep eutectic solventpyrano[2,3-c]pyrazolepyrazole

Identifiers

PMID38435668
PMCPMC10904593
OpenAlexW4391880392

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.