Evidence map›Paper›PMID 38435469›Full record

ArticleAPL bioengineering2024

Multifunctional scaffolds for biomedical applications: Crafting versatile solutions with polycaprolactone enriched by graphene oxide.

G Friggeri, I Moretti, F Amato, A G Marrani, F Sciandra, S G Colombarolli, A Vitali, S Viscuso, A Augello, L Cui and 4 more

Open access · goldAbstract read
In one paragraph

Article in APL bioengineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Let's Print an Ecology in 3D (and 4D).Materials (Basel, Switzerland) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

I MorettiDipartimento di Neuroscienze, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Roma, Italy.ORCID https://orcid.org/0009-0004-9706-5587
F AmatoDipartimento di Chimica, Università di Roma "La Sapienza," p.le A. Moro 5, I-00185 Roma, Italy.ORCID https://orcid.org/0000-0003-1577-7421
A G MarraniDipartimento di Chimica, Università di Roma "La Sapienza," p.le A. Moro 5, I-00185 Roma, Italy.ORCID https://orcid.org/0000-0002-3203-9642
F SciandraIstituto di Scienze e Tecnologie Chimiche "Giulio Natta"-SCITEC (CNR), C/O Istituto di Biochimica e Biochimica Clinica, Università Cattolica del Sacro Cuore, L.go F. Vito 1, 00168-Roma, Italy.ORCID https://orcid.org/0000-0002-2123-1516
S G ColombarolliIstituto di Scienze e Tecnologie Chimiche "Giulio Natta"-SCITEC (CNR), C/O Istituto di Biochimica e Biochimica Clinica, Università Cattolica del Sacro Cuore, L.go F. Vito 1, 00168-Roma, Italy.ORCID https://orcid.org/0000-0003-1526-2540
A VitaliIstituto di Scienze e Tecnologie Chimiche "Giulio Natta"-SCITEC (CNR), C/O Istituto di Biochimica e Biochimica Clinica, Università Cattolica del Sacro Cuore, L.go F. Vito 1, 00168-Roma, Italy.ORCID https://orcid.org/0000-0001-9828-4117
S ViscusoIstituto di Scienze e Tecnologie Chimiche "Giulio Natta"-SCITEC (CNR), C/O Istituto di Biochimica e Biochimica Clinica, Università Cattolica del Sacro Cuore, L.go F. Vito 1, 00168-Roma, Italy.ORCID https://orcid.org/0009-0000-7355-6032
L CuiDipartimento di Neuroscienze, Università Cattolica del Sacro Cuore, Largo Francesco Vito 1, 00168 Roma, Italy.ORCID https://orcid.org/0000-0001-7647-1376
Università Cattolica del Sacro Cuore · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The pressing need for multifunctional materials in medical settings encompasses a wide array of scenarios, necessitating specific tissue functionalities. A critical challenge is the occurrence of biofouling, particularly by contamination in surgical environments, a common cause of scaffolds impairment. Beyond the imperative to avoid infections, it is also essential to integrate scaffolds with living cells to allow for tissue regeneration, mediated by cell attachment. Here, we focus on the development of a versatile material for medical applications, driven by the diverse time-definite events after scaffold implantation. We investigate the potential of incorporating graphene oxide (GO) into polycaprolactone (PCL) and create a composite for 3D printing a scaffold with time-controlled antibacterial and anti-adhesive growth properties. Indeed, the as-produced PCL-GO scaffold displays a local hydrophobic effect, which is translated into a limitation of biological entities-attachment, including a diminished adhesion of bacteriophages and a reduction of

Identifiers

PMID38435469
PMCPMC10908559
OpenAlexW4392358125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.