Evidence map›Paper›PMID 38435029›Full record

ArticleOnco2023

Transcriptome Analysis Identifies Tumor Immune Microenvironment Signaling Networks Supporting Metastatic Castration-Resistant Prostate Cancer.

Lawrence P McKinney, Rajesh Singh, I King Jordan, Sooryanarayana Varambally, Eric B Dammer, James W Lillard

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Onco, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lawrence P McKinneyDepartment of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, Atlanta, GA 30310, USA.ORCID 0000-0002-9290-8336
Rajesh SinghDepartment of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, Atlanta, GA 30310, USA.ORCID 0000-0002-0397-3794
I King JordanSchool of Biological Sciences, Georgia Institute of Technology, Atlanta, GA 30332, USA.ORCID 0000-0003-4996-2203
Sooryanarayana VaramballyDivision of Molecular and Cellular Pathology, Department of Pathology, The University of Alabama at Birmingham, Birmingham, AL 35233, USA.
Eric B DammerDepartment of Biochemistry Emory, University School of Medicine, Atlanta, GA 30329, USA.ORCID 0000-0003-2947-7606
James W LillardDepartment of Microbiology, Biochemistry, and Immunology, Morehouse School of Medicine, Atlanta, GA 30310, USA.

Funding

TRANSCRIPTION FACTORS AND PROSTATE CANCERG12RR003034 · NCRR · MOREHOUSE SCHOOL OF MEDICINE · PI LILLARD, JAMES W · 1986 to 2011
$32.4M
Research Training & Career Development ProgramU54CA118638 · NCI · MOREHOUSE SCHOOL OF MEDICINE · PI Desiree Avia Rivers · 2005 to 2026
$22.7M
CANCER PREVENTION EDUCAT--STUDENT RESEARCH EXPERIENCESR25CA056452 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Shine Chang · 1992 to 2026
$6.9M
RENOV OF MEDICAL SCI &EDUCATION BLDGS: RETINAL CELLSC06RR018386 · NCRR · MOREHOUSE SCHOOL OF MEDICINE · PI SULLIVAN, LOUIS W. · 2002 to 2002
$1.3M
NCI NIH HHS R25 CA056452NCI NIH HHS U54 CA118638NCRR NIH HHS C06 RR018386NCRR NIH HHS G12 RR003034
6 · The paper itself

Abstract

Prostate cancer (PCa) is the second most common cause of cancer death in American men. Metastatic castration-resistant prostate cancer (mCRPC) is the most lethal form of PCa and preferentially metastasizes to the bones through incompletely understood molecular mechanisms. Herein, we processed RNA sequencing data from patients with mCRPC (

Indexed as

metastasisprostate cancersignalingtranscriptomicstumor microenvironment

Identifiers

PMID38435029
PMCPMC10906979

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.